This repository provides code and analyses as used in Xu, Ramos, Marshall & Doe (2023) Notch signaling and Bsh homeodomain activity are integrated to diversify Drosophila lamina neuron types, eLife (in press).
The analysis uses CATaDa (i.e. Dam-only binding data) and Bsh TaDa binding data, combined with existing scRNA-seq data, to discover gene expression and motif enrichment associated with Bsh in L4 neurons. The plots generated here were used in Figure 6 and Figure 6 -- figure supplement in the paper.
The full analysis code and output can be viewed as a pre-rendered HTML document, or you can clone the repository and run the Rmd document in Rstudio to generate the analysis and figures.