scAR (single-cell Ambient Remover) is a tool for denoising the ambient signals in droplet-based single cell omics. It can be used for multiple tasks, such as, sgRNA assignment for scCRISPRseq, identity barcode assignment for cell indexing, protein denoising for CITE-seq, mRNA denoising for scRNAseq, and etc..
- Installation, Usages and Tutorials can be found in the documentation.
- If you'd like to contribute, please read contributing guidelines.
- Please use the issues to submit bug reports.
This project is licensed under the terms of License.
Copyright 2022 Novartis International AG.
If you use scAR in your research, please consider citing our manuscript,
@article {Sheng2022.01.14.476312,
author = {Sheng, Caibin and Lopes, Rui and Li, Gang and Schuierer, Sven and Waldt, Annick and Cuttat, Rachel and Dimitrieva, Slavica and Kauffmann, Audrey and Durand, Eric and Galli, Giorgio G and Roma, Guglielmo and de Weck, Antoine},
title = {Probabilistic modeling of ambient noise in single-cell omics data},
elocation-id = {2022.01.14.476312},
year = {2022},
doi = {10.1101/2022.01.14.476312},
publisher = {Cold Spring Harbor Laboratory},
URL = {https://www.biorxiv.org/content/early/2022/01/14/2022.01.14.476312},
eprint = {https://www.biorxiv.org/content/early/2022/01/14/2022.01.14.476312.full.pdf},
journal = {bioRxiv}
}