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QMAP-Seq code for converting fastq files into relative cell numbers, plotting dose-response curves, calculating AUCs, and generating chemical-genetic interaction networks. Code Ocean capsule: https://codeocean.com/capsule/3022355/tree/v1 Original publication describing method: https://www.nature.com/articles/s41467-020-19553-8

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QMAP-Seq

QMAP-Seq code for converting fastq files into relative cell numbers, plotting dose-response curves, calculating AUCs, and generating chemical-genetic interaction networks.

First, fastq files are converted into relative cell numbers.

Once relative cell numbers are calculated for each combination, the data can be aggregated into one concatenated table (concatenate.R). The concatenated dataframe can then be transformed (tidy.R) and used to identify hits (test.R).

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QMAP-Seq code for converting fastq files into relative cell numbers, plotting dose-response curves, calculating AUCs, and generating chemical-genetic interaction networks. Code Ocean capsule: https://codeocean.com/capsule/3022355/tree/v1 Original publication describing method: https://www.nature.com/articles/s41467-020-19553-8

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