Repository associated to the "Epigenetic inactivation of the 5-methylcytosine RNA methyltransferase NSUN7 is associated with clinical outcome and threrapeutic vulnerability in liver cancer"
Interactome folder
-"PSM_CalculationV2.0.R" and "SAINTFilesCreatorV2.0.R" are necessary to obtain the final list of potential interactors and their asociated statistics parameters.
-First, run the "PSM_CalculationV2.0.R" script -Second, run the "SAINTFilesCreatorV2.0.R" script
The instructions to run each script are included in the R code.
Total Proteome folder
-Run the script called "TotalProteomeAnalysisSNU.R" to execute the analysis fo the total proteome. The script needs a function called "REMOVALcontaminantsPEAKS.R" and the file "contaminants.fasta" which are also included in the github.