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Voriconazole-PBPK

Instructions:

  1. Make script your working directory using the setwd() function.
  2. Run the script/pkgSetup.R script to install required packages.
  3. Run the code chunks in the script/script.R script to compile models, run simulations and other analyses and reproduce manuscript figures.
  4. Run script/runSobol.R script to run the Sobol global sensitivity analysis and reproduce Figure S1. CAUTION: This script takes several hours to run.

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