Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

detached otolithic membrane MP:0003145 - revise definition and EQ #3969

Closed
anna-anagnostop opened this issue Apr 25, 2024 · 1 comment
Closed
Assignees

Comments

@anna-anagnostop
Copy link
Collaborator

anna-anagnostop commented Apr 25, 2024

detached otolithic membrane MP:0003145 is currently defined as:

CURRENT DEF: The otolithic (otoconial) membrane is abnormally detached from the underlying neuroepithelium

Current EQ is incorrect:
has part some (detached from and (towards some otolithic part of statoconial membrane) and (has modifier some abnormal))

Amend definition to read as:
SUGGESTED DEF: part or all of the otolithic (otoconial) membrane is abnormally separated from the sensory epithelium (macula) of the utricle and/or saccule
Cross-reference: PMID: 22116368

EQ needs to use abnormallyDetachedAnatomicalEntity pattern (which must first be corrected to use singular form in pattern name and 'detached from' PATO_0001453 instead of just 'detached' (reopen uPheno issue #692 )

Should the EQ be using characteristic of part of?

@anna-anagnostop
Copy link
Collaborator Author

anna-anagnostop commented Apr 29, 2024

Definition has been amended as suggested above.

Incorrect EQ has been removed; correct EQ will be updated once the relevant pattern has been fixed.

EQ will use anatomical_entity_detached_from = vestibular epithelium, a higher level term that covers both the 'epithelium of saccule' and 'epithelium of utricle" (EQ can't do an "and/or")

Per Sue: "I don't think this would be 'characteristic of part of'. We wouldn't want to say for example that a detached retina was a detached eye"; see obophenotype/upheno#692

@anna-anagnostop anna-anagnostop self-assigned this Jun 5, 2024
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

1 participant