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Analysis of RNA folding bias (Local Folding Energy) based on randomizations

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michaelpeeri/rnafold-public

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Perform analysis of mRNA folding bias (Local Folding Energy) based on randomization experiments. See publication (Peeri and Tuller 2020) for description of methods.

Important source files:

  • taxonomy.py -- Create multiple-species plots, based on taxonomic tree or PCA

  • profile_plots.py -- Create plot for individual species

  • tree_traits_effects_analysis_with_taxgroups.r -- Perform GLS regression and other analyses for multiple species based on phylogenetic tree

  • config.py -- Configuration parameters (including database connections, etc.)

  • r-rnafold -- Singularity recipe for initializing container with R environment

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Analysis of RNA folding bias (Local Folding Energy) based on randomizations

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