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Censored Linear Models

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censlm

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The goal of censlm is to simplify fitting censored linear models and using them to draw plausible imputed values for censored observations.

Installation

You can install the development version of censlm like so:

remotes::install_github("mikmart/censlm")

Example

Fit a censored linear model to left-censored data with clm(), then draw random values for censored observations from the fitted distribution with imputed():

library(censlm)
#> Loading required package: survival
set.seed(42)

# Simulate left-censored log-normal CRP observations
crp <- rlnorm(10000, 1.355, 1.450)
lloq <- 3
obs <- replace(crp, crp < lloq, lloq)
crpdf <- data.frame(crp, lloq, obs)

# Fit censored linear model and extract (random) imputations
fit <- clm(log(obs) ~ 1, left = log(lloq))
imp <- exp(imputed(fit))

summary(fit)
#> 
#> Call:
#> survreg(formula = Surv(log(obs), log(obs) > log(lloq), type = "left") ~ 
#>     1, dist = "gaussian")
#>              Value Std. Error    z      p
#> (Intercept) 1.3421     0.0168 79.8 <2e-16
#> Log(scale)  0.3749     0.0103 36.3 <2e-16
#> 
#> Scale= 1.45 
#> 
#> Gaussian distribution
#> Loglik(model)= -13460.2   Loglik(intercept only)= -13460.2
#> Number of Newton-Raphson Iterations: 4 
#> n= 10000
summary(cbind(crpdf, imp))
#>       crp                lloq        obs                imp           
#>  Min.   :   0.011   Min.   :3   Min.   :   3.000   Min.   :   0.0056  
#>  1st Qu.:   1.418   1st Qu.:3   1st Qu.:   3.000   1st Qu.:   1.4200  
#>  Median :   3.842   Median :3   Median :   3.842   Median :   3.8418  
#>  Mean   :  11.158   Mean   :3   Mean   :  11.883   Mean   :  11.1576  
#>  3rd Qu.:  10.139   3rd Qu.:3   3rd Qu.:  10.139   3rd Qu.:  10.1394  
#>  Max.   :2060.559   Max.   :3   Max.   :2060.559   Max.   :2060.5585

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