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I have a set of fasta files with reference sequences of V, D, J or C genes.
Each file is padded with . symbols or something similar to align anchor points. So each anchor point has the same position in all sequences. (exactly like IMGT gaps)
There is file or command-line argument with positions of all anchor points. Something like this:
V=108:117:125:148:157: etc...
I can create new loci library from this information or append it to already existing one:
User story 1 (from IMGT-like reference):
I have a set of fasta files with reference sequences of V, D, J or C genes.
Each file is padded with
.
symbols or something similar to align anchor points. So each anchor point has the same position in all sequences. (exactly like IMGT gaps)There is file or command-line argument with positions of all anchor points. Something like this:
I can create new loci library from this information or append it to already existing one:
this will create
myLL.ll
file or add locus information to it if it already exists.taxonId
,locus
andgeneName
.User story 2 (library from genomic data, MiXCR way of LL creation):
I have a big fasta file with genomic sequence of chromosome or particular locus.
There is another file with tab-delimited list of reference genes. Example
segments.txt
:I can create new loci library from this information or append it to already existing one:
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