updated transcript for ASXL2

[jjgao]

Looks like the mapping from Ensembl is incorrect. The RefSeq sequence has 1435 amino acids instead of 1407.

[ckandoth]

Thanks @jjgao. NM_018263.4 has 1407aa while NM_018263.5 has 1435aa. Since DMP is using the older one, that's what we are sticking with in isoform_overrides_at_mskcc. Lemme know what led you to this, and we can find an alternative solution.
(Update 8/7/2017 - The info above on aa lengths is incorrect.)

[ckandoth]

I'm gonna close this request. It exposed a larger problem that versioning of RefSeq isoforms needs to be implemented across the CMO, before we do another sync up.
(Update 8/7/2017 - This comment is also incorrect. See below for details on what really went wrong.)

[ckandoth]

Per my work notes matching ENST IDs to Refseq IDs used by MSKCC's clinical bioinformatics, an ENST ID for NM_018263.4 couldn't be automatically extracted via NCBI's CCDS. So I had manually looked it up in Ensembl's release 75 archives (the latest for GRCh37 loci, viewable at feb2014.archive.ensembl.org), where the xref_refseq mapping was incorrect, as JJ pointed out in the first comment. I went back and reviewed the 8 other genes for which I had manually looked up matching ENST isoforms, and found similar mistakes in 3 other genes. Updated those too. Will merge shortly.