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We have a ton of data using R9.4.1 (Kit 10) chemistry (eg. in the order of hundreds+ human samples) and would like to explore 5hmC calling. Is that possible with the new remora v2 models or do we have to use the older initial Remora ones? As far as I know those ones have substantially less accuracy?
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We do not have R9 5hmC Remora models with the latest algorithm updates. It is likely that these models could be improved slightly with algorithm updates, but the main upgrades are likely due to the pore and kit upgrade as well as upgrades to the training data preparation. I would recommend for older R9 data that the released models be used for 5hmC exploration.
We have a ton of data using R9.4.1 (Kit 10) chemistry (eg. in the order of hundreds+ human samples) and would like to explore 5hmC calling. Is that possible with the new remora v2 models or do we have to use the older initial Remora ones? As far as I know those ones have substantially less accuracy?
The text was updated successfully, but these errors were encountered: