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Tree construction with IQTree #4

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rvosa opened this issue Apr 11, 2020 · 1 comment
Closed

Tree construction with IQTree #4

rvosa opened this issue Apr 11, 2020 · 1 comment

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@rvosa
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rvosa commented Apr 11, 2020

IQTree is more or less the standard for building trees from viral genomes. A somewhat costly step that it does by default is to do full model testing to decide on the right model. Perhaps as per Rambaut et al. we might just settle on HKY85+G.

For the clade assignments, bootstrap support would be good (e.g. 1000 replicates), so experiment with how costly that is (-bnni parameter, I think).

@rvosa rvosa added this to the Full workflow milestone Apr 11, 2020
This was referenced Apr 11, 2020
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rvosa commented Apr 13, 2020

cipresrun \
    -t IQTREE_XSEDE \
    -p vparam.specify_runtype_=2 \
    -p vparam.specify_dnamodel_=HKY \
    -p vparam.bootstrap_type_=bb \
    -p vparam.use_bnni_=1 \
    -p vparam.num_bootreps_=1000 \
    -p vparam.specify_numparts_=1 \
    -i concatenated.fasta.961.fasta.aln \
    -o output.contree

@rvosa rvosa closed this as completed in fd3e51b Apr 13, 2020
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