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from neuron import h, gui | ||
from neuron.units import ms, mV | ||
h.load_file('stdrun.hoc') | ||
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class Cell: | ||
def __init__(self, gid, x, y, z, theta): | ||
self._gid = gid | ||
self._setup_morphology() | ||
self.all = self.soma.wholetree() | ||
self._setup_biophysics() | ||
self.x = self.y = self.z = 0 | ||
h.define_shape() | ||
self._rotate_z(theta) | ||
self._set_position(x, y, z) | ||
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# everything below here in this method is NEW | ||
self._spike_detector = h.NetCon(self.soma(0.5)._ref_v, None, sec=self.soma) | ||
self.spike_times = h.Vector() | ||
self._spike_detector.record(self.spike_times) | ||
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self._ncs = [] | ||
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self.soma_v = h.Vector().record(self.soma(0.5)._ref_v) | ||
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def __repr__(self): | ||
return '{}[{}]'.format(self.name, self._gid) | ||
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def _set_position(self, x, y, z): | ||
for sec in self.all: | ||
for i in range(sec.n3d()): | ||
sec.pt3dchange(i, | ||
x - self.x + sec.x3d(i), | ||
y - self.y + sec.y3d(i), | ||
z - self.z + sec.z3d(i), | ||
sec.diam3d(i)) | ||
self.x, self.y, self.z = x, y, z | ||
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def _rotate_z(self, theta): | ||
"""Rotate the cell about the Z axis.""" | ||
for sec in self.all: | ||
for i in range(sec.n3d()): | ||
x = sec.x3d(i) | ||
y = sec.y3d(i) | ||
c = h.cos(theta) | ||
s = h.sin(theta) | ||
xprime = x * c - y * s | ||
yprime = x * s + y * c | ||
sec.pt3dchange(i, xprime, yprime, sec.z3d(i), sec.diam3d(i)) | ||
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class BallAndStick(Cell): | ||
name = 'BallAndStick' | ||
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def _setup_morphology(self): | ||
self.soma = h.Section(name='soma', cell=self) | ||
self.dend = h.Section(name='dend', cell=self) | ||
self.dend.connect(self.soma) | ||
self.soma.L = self.soma.diam = 12.6157 | ||
self.dend.L = 200 | ||
self.dend.diam = 1 | ||
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def _setup_biophysics(self): | ||
for sec in self.all: | ||
sec.Ra = 100 # Axial resistance in Ohm * cm | ||
sec.cm = 1 # Membrane capacitance in micro Farads / cm^2 | ||
self.soma.insert('hh') | ||
for seg in self.soma: | ||
seg.hh.gnabar = 0.12 # Sodium conductance in S/cm2 | ||
seg.hh.gkbar = 0.036 # Potassium conductance in S/cm2 | ||
seg.hh.gl = 0.0003 # Leak conductance in S/cm2 | ||
seg.hh.el = -54.3 # Reversal potential in mV | ||
# Insert passive current in the dendrite | ||
self.dend.insert('pas') | ||
for seg in self.dend: | ||
seg.pas.g = 0.001 # Passive conductance in S/cm2 | ||
seg.pas.e = -65 # Leak reversal potential mV | ||
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# NEW: the synapse | ||
self.syn = h.ExpSyn(self.dend(0.5)) | ||
self.syn.tau = 2 * ms | ||
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