Code for simulation and figure plotting for "Loss or Gain of Function? Effects of Ion Channel Mutations on Neuronal Firing Depend on the Neuron Type" by Koch et al. 2023. https://doi.org/10.3389/fneur.2023.1194811 Modelling on the effects of ion current property changes on firing behaviour in diverse neuronal models and in with episodic ataxia type 1 associated KCNA1 mutations.
-
./Code
Python code for simulations and analysis../Code/run_simulations.sh
Bash shell script to run all simulations and analysis./Code/Functions
All functions for all neuronal models./Code/Neuron_models
Scripts to run each neuronal models./Code/Sensitivity_Analysis
Scripts to run sensitivity analysis for each neuronal models./Code/KCNA1_mutations
Scripts to simulate all KCNA1 mutations in each neuronal models./Code/csv_generation
Scripts for additionaly analysis and to make .csv files needed for plottting
-
./Figures
Figures and python files for generating them./Figures/Data
Data used to plot figures