Merge pull request #403 from nlmixr2/402-nlm

402 nlm

NAMESPACE

@@ -30,6 +30,7 @@ S3method(getValidNlmixrCtl,fo)
 S3method(getValidNlmixrCtl,foce)
 S3method(getValidNlmixrCtl,focei)
 S3method(getValidNlmixrCtl,foi)
+S3method(getValidNlmixrCtl,nlm)
 S3method(getValidNlmixrCtl,nlme)
 S3method(getValidNlmixrCtl,posthoc)
 S3method(getValidNlmixrCtl,rxSolve)
@@ -57,6 +58,7 @@ S3method(nlmixr2Est,fo)
 S3method(nlmixr2Est,foce)
 S3method(nlmixr2Est,focei)
 S3method(nlmixr2Est,foi)
+S3method(nlmixr2Est,nlm)
 S3method(nlmixr2Est,nlme)
 S3method(nlmixr2Est,output)
 S3method(nlmixr2Est,posthoc)
@@ -130,6 +132,7 @@ S3method(nmObjGetControl,fo)
 S3method(nmObjGetControl,foce)
 S3method(nmObjGetControl,focei)
 S3method(nmObjGetControl,foi)
+S3method(nmObjGetControl,nlm)
 S3method(nmObjGetControl,nlme)
 S3method(nmObjGetControl,posthoc)
 S3method(nmObjGetControl,saem)
@@ -157,6 +160,7 @@ S3method(nmObjGetPredOnly,saem)
 S3method(nmObjGetRxSolve,default)
 S3method(nmObjHandleControlObject,default)
 S3method(nmObjHandleControlObject,foceiControl)
+S3method(nmObjHandleControlObject,nlmControl)
 S3method(nmObjHandleControlObject,nlmeControl)
 S3method(nmObjHandleControlObject,saemControl)
 S3method(nmObjHandleModelObject,default)
@@ -209,9 +213,15 @@ S3method(rxUiGet,foceiThetaS)
 S3method(rxUiGet,getEBEEnv)
 S3method(rxUiGet,getSplitMuModel)
 S3method(rxUiGet,loadPrune)
+S3method(rxUiGet,loadPruneNlm)
 S3method(rxUiGet,loadPruneSaem)
 S3method(rxUiGet,loadPruneSaemPred)
 S3method(rxUiGet,loadPruneSens)
+S3method(rxUiGet,nlmModel0)
+S3method(rxUiGet,nlmParIni)
+S3method(rxUiGet,nlmParName)
+S3method(rxUiGet,nlmParNameFun)
+S3method(rxUiGet,nlmRxModel)
 S3method(rxUiGet,nlmeFD)
 S3method(rxUiGet,nlmeFixedFormula)
 S3method(rxUiGet,nlmeFunction)
@@ -286,6 +296,7 @@ export("%>%")
 export(.foceiPreProcessData)
 export(.nlmixr2estLastPredSimulationInfo)
 export(.nlmixr2objectNameAssign)
+export(.nlmixrNlmFun)
 export(.nlmixrNlmeFun)
 export(.rxGetDVFTransform)
 export(.saemDropMuRefFromModel)
@@ -327,6 +338,7 @@ export(ini)
 export(logit)
 export(lotri)
 export(model)
+export(nlmControl)
 export(nlme)
 export(nlmeControl)
 export(nlmixr)

NEWS.md

@@ -1,5 +1,13 @@
 # nlmixr2est (development version)
 
+## New Features
+
+- Algebraic mu referencing has been implemented in `nlme` and `saem`.
+
+- New estimation method "nlm" has been added to estimate population
+  only likelihoods using `stats::nlm` and possibly return a
+  standardized `nlmixr2` fit.
+
 ## Breaking changes
 
 - Removed `fit$saemTransformedData` since it isn't actually used in
@@ -10,9 +18,6 @@
   lag features need to translate the data differently based on
   `rxControl()` options.
 
-## mu referencing
-
-- Algebraic mu referencing has been implemented in `nlme` and `saem`.
 
 ## Bug fixes