new term request: profundal placode

[ANiknejad]

Hi Chris,

Currently we only have this term for 'profundal' stuff:

id: XAO:0004093
name: profundal placode (Xenopus)

'profundal placode' sounds to be egal to 'ophtalmic placode'
http://www.ncbi.nlm.nih.gov/pubmed/?term=22512454
" [In vertebrates] The lens placode, which generates the crystalline-containing cells of the lens, is also associated with the forebrain but forms more posteriorly alongside the region of the diencephalon that will give rise to the optic cup. More caudally, the trigeminal placodes, the ophthalmic (or profundal) and maxillomandibular, emerge at the level of the midbrain-hindbrain boundary....clearly distinct profundal and trigeminal placodes giving rise to correspondingly distinct ganglia are readily observable in shark embryos (O’Neill et al. 2007)."

In Uberon we have an 'optic placode' exact synonym of
UBERON:0003071
name: eye primordium

However I guess, that does not match the 'profundal placode' as defined here for Shark
http://www.ncbi.nlm.nih.gov/pubmed/?term=17234174

Cheers,

Anne

[cmungall]

Interesting. See also: UBERON:0003070 ! trigeminal placode

Figure 9-5 of Butler and Hodos seems to use Profundal as synonymous with trigeminal... but this may only be true of their distal end; from XAO: "The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24"

[mellybelly]

The placodes are notoriously diverse across species. here is a great review with many key citations:
http://www.ncbi.nlm.nih.gov/books/NBK53171/

[cmungall]

See this

for a first pass.

In this model we have a single class for each 'lobe' of the trigeminal complex, whether that 'lobe' is completely fused, partly fused or a distinct ganglion unto itself. We could split this and have separate classes, and then link via a cross-class homology assertion, but this seems like inflation.

The ontology is more complex than the diagram as we follow EMAPA in introducing an intermediate 'preganglion', but if this does no work for us should we merge it?

Nerves need work.

[gouttegd]

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