opentiva is a free and open-source python module that simulates target controlled infusions by using mathematical models relating to the pharmacokinetic and pharmacodynamic compartment models of drugs used in anaesthetic practice.
Usage examples can be found in the examples directory.
Example web app using the module can be found at opentiva.com
Full documentation can be found here
- Plasma and effect site targeting
- One, two and three compartment modelling
- Built in Pk/Pd models from a range of drugs
- Tpeak ke0 calcuation
- User defined infusions
- Optional k20 elimination in two compartment modelling
- Customize a range of properties relating to the targetting and maintenance methods
Install opentiva by running:
pip install opentiva
- Issue Tracker: github.com/opentiva/opentiva/issues
- Source Code: github.com/opentiva/opentiva
If you are having issues, please let us know via github or opentiva@jpselby.co.uk.
Support opentiva by donating to:
opentiva is for informational, research and educational purposes only. The pharmacokinetic/ pharmacodynamics are all obtained from medical literature and infusions resulting from these can vary widely. The user assumes all risks from the use of this application for clinical purposes.
The project is licensed under the MIT license.