Impact of COVID-19 vaccination on preventing long COVID: A population-based cohort study using linked NHS data 

Background: While vaccines have shown impressive efficacy to prevent severe COVID-19, their impact on preventing long COVID is not investigated in ongoing trials.  

Objective: To evaluate the impact of covid vaccination on the prevention of long COVID using UK primary care data.

Study Part 1A: Characterising Long COVID

• Analytics use case(s): Characterization
• Study type: Clinical Application
• Tags: OHDSI
• Study lead: Prof. Daniel Prieto-Alhambra, Dr. Annika Jödicke, Kristin Kostka
• Study lead forums tag: daniel_prieto, annika_joedicke, krfeeney
• Study start date: 1st October 2021
• Study end date: TBD
• Protocol: To be uploaded
• Publications: N/A
• Results explorer: Long COVID Cohort Diagnostics App

Instructions

Under Iterative Versions, there is a single R file (longCOVID-CD-11MAY2022.R) that contains the CohortDiagnostics run. The current code runs using a public WebAPI and is dependent on OHDSI libraries CohortDiagnostics (using Release v2.2.4) and DatabaseConnector (using Release v5.0.2).

Note: eventually we'll have to change this to be a self-contained R package but the current approach pulls from a public WebAPI that, provided a user can access the internet, should be executable in your local environment. Updates will be made as bandwidth permits.