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Code deposited for paper "Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action", Kintses et al. Nature Communications

pappb/Kintses-et-al-AMP-Chemogenomics-NatComm

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Kintses-et-al-AMP-Chemogenomics-NatComm

Code deposited for paper "Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action", Kintses et al. Nature Communications

The programs are written in R.

script folder

  • script/cg01_RemoveBackground.R
  • script/cg02_rescaleData.R
  • script/cg03_plotsOfDataAfterBgRemoveAndRescale.R Generates figures to visualise data grouped by treatments. It is not needed for further analysis.
  • script/cg04_plotRawBarplotsForEachLine.R Generates figures to visualise data grouped by genes. It is not needed for further analysis.
  • script/cg05_normalizationOfBimodalDist.R Normalizes data.
  • script/functions-for-chemogenomic-project.R Contains some helper functions.
  • script/pdfTools.R Contains some additional helper functions for the normalization script.

data folder

  • It contains the input files of the scripts
  • data/dataTable1-expression_values_of_sequencing.csv - this file contains the read numbers from the sequencing
  • data/batch-structure.csv - this table describes which data columns come from the same assay
  • all the intermediate data tables will be placed here.

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Code deposited for paper "Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action", Kintses et al. Nature Communications

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