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RELICS1.0

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@patfiaux patfiaux released this 17 Jan 20:04
· 161 commits to master since this release
02c11b2

RELICS1.0 (https://www.biorxiv.org/content/10.1101/687293v1.full) is a tool for analyzing CRISPR regulatory screens. Given a set of guides to train on, RELICS uses a generalized linear mixed model (GLMM) to identify regions with high similarity to the regulatory (enhancer-like) guides and regions which are more similar to non-regulatory (negative controls) guides.