RELICS1.0
RELICS1.0 (https://www.biorxiv.org/content/10.1101/687293v1.full) is a tool for analyzing CRISPR regulatory screens. Given a set of guides to train on, RELICS uses a generalized linear mixed model (GLMM) to identify regions with high similarity to the regulatory (enhancer-like) guides and regions which are more similar to non-regulatory (negative controls) guides.