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mapk53.an
229 lines (227 loc) · 8.1 KB
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mapk53.an
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"AKT" [0, 1]
"AP1" [0, 1]
"ATF2" [0, 1]
"ATM" [0, 1]
"Apoptosis" [0, 1]
"BCL2" [0, 1]
"CREB" [0, 1]
"DNA_damage" [0, 1]
"DUSP1" [0, 1]
"EGFR" [0, 1]
"EGFR_stimulus" [0, 1]
"ELK1" [0, 1]
"ERK" [0, 1]
"FGFR3" [0, 1]
"FGFR3_stimulus" [0, 1]
"FOS" [0, 1]
"FOXO3" [0, 1]
"FRS2" [0, 1]
"GAB1" [0, 1]
"GADD45" [0, 1]
"GRB2" [0, 1]
"Growth_Arrest" [0, 1]
"JNK" [0, 1]
"JUN" [0, 1]
"MAP3K1_3" [0, 1]
"MAX" [0, 1]
"MDM2" [0, 1]
"MEK1_2" [0, 1]
"MSK" [0, 1]
"MTK1" [0, 1]
"MYC" [0, 1]
"PDK1" [0, 1]
"PI3K" [0, 1]
"PKC" [0, 1]
"PLCG" [0, 1]
"PPP2CA" [0, 1]
"PTEN" [0, 1]
"Proliferation" [0, 1]
"RAF" [0, 1]
"RAS" [0, 1]
"RSK" [0, 1]
"SMAD" [0, 1]
"SOS" [0, 1]
"SPRY" [0, 1]
"TAK1" [0, 1]
"TAOK" [0, 1]
"TGFBR" [0, 1]
"TGFBR_stimulus" [0, 1]
"p14" [0, 1]
"p21" [0, 1]
"p38" [0, 1]
"p53" [0, 1]
"p70" [0, 1]
"AKT" 0 -> 1 when "PDK1"=1 and "PTEN"=0
"AKT" 1 -> 0 when "PDK1"=0
"AKT" 1 -> 0 when "PTEN"=1
"AP1" 0 -> 1 when "ATF2"=0 and "FOS"=1 and "JUN"=1
"AP1" 0 -> 1 when "ATF2"=1 and "JUN"=1
"AP1" 1 -> 0 when "ATF2"=0 and "FOS"=0
"AP1" 1 -> 0 when "JUN"=0
"ATF2" 0 -> 1 when "JNK"=1
"ATF2" 0 -> 1 when "p38"=1
"ATF2" 1 -> 0 when "JNK"=0 and "p38"=0
"ATM" 0 -> 1 when "DNA_damage"=1
"ATM" 1 -> 0 when "DNA_damage"=0
"Apoptosis" 0 -> 1 when "BCL2"=0 and "ERK"=0 and "FOXO3"=1 and "p53"=1
"Apoptosis" 1 -> 0 when "BCL2"=1
"Apoptosis" 1 -> 0 when "ERK"=1
"Apoptosis" 1 -> 0 when "FOXO3"=0
"Apoptosis" 1 -> 0 when "p53"=0
"BCL2" 0 -> 1 when "AKT"=1 and "CREB"=1
"BCL2" 1 -> 0 when "AKT"=0
"BCL2" 1 -> 0 when "CREB"=0
"CREB" 0 -> 1 when "MSK"=1
"CREB" 1 -> 0 when "MSK"=0
"DUSP1" 0 -> 1 when "CREB"=1
"DUSP1" 1 -> 0 when "CREB"=0
"EGFR" 0 -> 1 when "EGFR_stimulus"=0 and "GRB2"=0 and "PKC"=0 and "SPRY"=1
"EGFR" 0 -> 1 when "EGFR_stimulus"=1 and "GRB2"=0 and "PKC"=0
"EGFR" 1 -> 0 when "EGFR_stimulus"=0 and "SPRY"=0
"EGFR" 1 -> 0 when "GRB2"=1
"EGFR" 1 -> 0 when "PKC"=1
"ELK1" 0 -> 1 when "ERK"=1
"ELK1" 0 -> 1 when "JNK"=1
"ELK1" 0 -> 1 when "p38"=1
"ELK1" 1 -> 0 when "ERK"=0 and "JNK"=0 and "p38"=0
"ERK" 0 -> 1 when "MEK1_2"=1
"ERK" 1 -> 0 when "MEK1_2"=0
"FGFR3" 0 -> 1 when "FGFR3_stimulus"=1 and "GRB2"=0 and "PKC"=0
"FGFR3" 1 -> 0 when "FGFR3_stimulus"=0
"FGFR3" 1 -> 0 when "GRB2"=1
"FGFR3" 1 -> 0 when "PKC"=1
"FOS" 0 -> 1 when "CREB"=0 and "ELK1"=1 and "ERK"=1 and "RSK"=1
"FOS" 0 -> 1 when "CREB"=1 and "ERK"=1 and "RSK"=1
"FOS" 1 -> 0 when "CREB"=0 and "ELK1"=0
"FOS" 1 -> 0 when "ERK"=0
"FOS" 1 -> 0 when "RSK"=0
"FOXO3" 0 -> 1 when "AKT"=0 and "JNK"=1
"FOXO3" 1 -> 0 when "AKT"=1
"FOXO3" 1 -> 0 when "JNK"=0
"FRS2" 0 -> 1 when "FGFR3"=1 and "GRB2"=0 and "SPRY"=0
"FRS2" 1 -> 0 when "FGFR3"=0
"FRS2" 1 -> 0 when "GRB2"=1
"FRS2" 1 -> 0 when "SPRY"=1
"GAB1" 0 -> 1 when "GRB2"=1
"GAB1" 0 -> 1 when "PI3K"=1
"GAB1" 1 -> 0 when "GRB2"=0 and "PI3K"=0
"GADD45" 0 -> 1 when "SMAD"=1
"GADD45" 0 -> 1 when "p53"=1
"GADD45" 1 -> 0 when "SMAD"=0 and "p53"=0
"GRB2" 0 -> 1 when "EGFR"=1
"GRB2" 0 -> 1 when "FRS2"=1
"GRB2" 0 -> 1 when "TGFBR"=1
"GRB2" 1 -> 0 when "EGFR"=0 and "FRS2"=0 and "TGFBR"=0
"Growth_Arrest" 0 -> 1 when "p21"=1
"Growth_Arrest" 1 -> 0 when "p21"=0
"JNK" 0 -> 1 when "DUSP1"=0 and "MAP3K1_3"=1
"JNK" 0 -> 1 when "DUSP1"=0 and "MTK1"=1
"JNK" 0 -> 1 when "DUSP1"=0 and "TAK1"=1
"JNK" 0 -> 1 when "DUSP1"=0 and "TAOK"=1
"JNK" 0 -> 1 when "DUSP1"=1 and "MAP3K1_3"=0 and "MTK1"=0 and "TAK1"=1 and "TAOK"=1
"JNK" 0 -> 1 when "DUSP1"=1 and "MAP3K1_3"=0 and "MTK1"=1 and "TAK1"=1
"JNK" 0 -> 1 when "DUSP1"=1 and "MAP3K1_3"=0 and "MTK1"=1 and "TAOK"=1
"JNK" 0 -> 1 when "DUSP1"=1 and "MAP3K1_3"=1 and "MTK1"=1
"JNK" 0 -> 1 when "DUSP1"=1 and "MAP3K1_3"=1 and "TAK1"=1
"JNK" 0 -> 1 when "DUSP1"=1 and "MAP3K1_3"=1 and "TAOK"=1
"JNK" 1 -> 0 when "DUSP1"=0 and "MAP3K1_3"=0 and "MTK1"=0 and "TAK1"=0 and "TAOK"=0
"JNK" 1 -> 0 when "DUSP1"=1 and "MAP3K1_3"=0 and "MTK1"=0 and "TAK1"=0
"JNK" 1 -> 0 when "DUSP1"=1 and "MAP3K1_3"=0 and "MTK1"=0 and "TAOK"=0
"JNK" 1 -> 0 when "DUSP1"=1 and "MAP3K1_3"=0 and "MTK1"=1 and "TAK1"=0 and "TAOK"=0
"JNK" 1 -> 0 when "DUSP1"=1 and "MAP3K1_3"=1 and "MTK1"=0 and "TAK1"=0 and "TAOK"=0
"JUN" 0 -> 1 when "JNK"=1
"JUN" 1 -> 0 when "JNK"=0
"MAP3K1_3" 0 -> 1 when "RAS"=1
"MAP3K1_3" 1 -> 0 when "RAS"=0
"MAX" 0 -> 1 when "p38"=1
"MAX" 1 -> 0 when "p38"=0
"MDM2" 0 -> 1 when "AKT"=0 and "p14"=0 and "p53"=1
"MDM2" 0 -> 1 when "AKT"=1 and "p14"=0
"MDM2" 1 -> 0 when "AKT"=0 and "p53"=0
"MDM2" 1 -> 0 when "p14"=1
"MEK1_2" 0 -> 1 when "AP1"=0 and "MAP3K1_3"=0 and "PPP2CA"=0 and "RAF"=1
"MEK1_2" 0 -> 1 when "AP1"=0 and "MAP3K1_3"=1 and "PPP2CA"=0
"MEK1_2" 1 -> 0 when "AP1"=1
"MEK1_2" 1 -> 0 when "MAP3K1_3"=0 and "RAF"=0
"MEK1_2" 1 -> 0 when "PPP2CA"=1
"MSK" 0 -> 1 when "ERK"=1
"MSK" 0 -> 1 when "p38"=1
"MSK" 1 -> 0 when "ERK"=0 and "p38"=0
"MTK1" 0 -> 1 when "GADD45"=1
"MTK1" 1 -> 0 when "GADD45"=0
"MYC" 0 -> 1 when "AKT"=0 and "MAX"=1 and "MSK"=1
"MYC" 0 -> 1 when "AKT"=1 and "MSK"=1
"MYC" 1 -> 0 when "AKT"=0 and "MAX"=0
"MYC" 1 -> 0 when "MSK"=0
"PDK1" 0 -> 1 when "PI3K"=1
"PDK1" 1 -> 0 when "PI3K"=0
"PI3K" 0 -> 1 when "GAB1"=1
"PI3K" 0 -> 1 when "RAS"=1 and "SOS"=1
"PI3K" 1 -> 0 when "GAB1"=0 and "RAS"=0
"PI3K" 1 -> 0 when "GAB1"=0 and "SOS"=0
"PKC" 0 -> 1 when "PLCG"=1
"PKC" 1 -> 0 when "PLCG"=0
"PLCG" 0 -> 1 when "EGFR"=1
"PLCG" 0 -> 1 when "FGFR3"=1
"PLCG" 1 -> 0 when "EGFR"=0 and "FGFR3"=0
"PPP2CA" 0 -> 1 when "p38"=1
"PPP2CA" 1 -> 0 when "p38"=0
"PTEN" 0 -> 1 when "p53"=1
"PTEN" 1 -> 0 when "p53"=0
"Proliferation" 0 -> 1 when "MYC"=1 and "p21"=0 and "p70"=1
"Proliferation" 1 -> 0 when "MYC"=0
"Proliferation" 1 -> 0 when "p21"=1
"Proliferation" 1 -> 0 when "p70"=0
"RAF" 0 -> 1 when "AKT"=0 and "ERK"=0 and "PKC"=1
"RAF" 0 -> 1 when "AKT"=0 and "ERK"=0 and "RAS"=1
"RAF" 1 -> 0 when "AKT"=1
"RAF" 1 -> 0 when "ERK"=1
"RAF" 1 -> 0 when "PKC"=0 and "RAS"=0
"RAS" 0 -> 1 when "PLCG"=1
"RAS" 0 -> 1 when "SOS"=1
"RAS" 1 -> 0 when "PLCG"=0 and "SOS"=0
"RSK" 0 -> 1 when "ERK"=1
"RSK" 1 -> 0 when "ERK"=0
"SMAD" 0 -> 1 when "TGFBR"=1
"SMAD" 1 -> 0 when "TGFBR"=0
"SOS" 0 -> 1 when "GRB2"=1 and "RSK"=0
"SOS" 1 -> 0 when "GRB2"=0
"SOS" 1 -> 0 when "RSK"=1
"SPRY" 0 -> 1 when "ERK"=1
"SPRY" 1 -> 0 when "ERK"=0
"TAK1" 0 -> 1 when "TGFBR"=1
"TAK1" 1 -> 0 when "TGFBR"=0
"TAOK" 0 -> 1 when "ATM"=1
"TAOK" 1 -> 0 when "ATM"=0
"TGFBR" 0 -> 1 when "TGFBR_stimulus"=1
"TGFBR" 1 -> 0 when "TGFBR_stimulus"=0
"p14" 0 -> 1 when "MYC"=1
"p14" 1 -> 0 when "MYC"=0
"p21" 0 -> 1 when "AKT"=0 and "p53"=1
"p21" 1 -> 0 when "AKT"=1
"p21" 1 -> 0 when "p53"=0
"p38" 0 -> 1 when "DUSP1"=0 and "MAP3K1_3"=1
"p38" 0 -> 1 when "DUSP1"=0 and "MTK1"=1
"p38" 0 -> 1 when "DUSP1"=0 and "TAK1"=1
"p38" 0 -> 1 when "DUSP1"=0 and "TAOK"=1
"p38" 0 -> 1 when "DUSP1"=1 and "MAP3K1_3"=0 and "MTK1"=0 and "TAK1"=1 and "TAOK"=1
"p38" 0 -> 1 when "DUSP1"=1 and "MAP3K1_3"=0 and "MTK1"=1 and "TAK1"=1
"p38" 0 -> 1 when "DUSP1"=1 and "MAP3K1_3"=0 and "MTK1"=1 and "TAOK"=1
"p38" 0 -> 1 when "DUSP1"=1 and "MAP3K1_3"=1 and "MTK1"=1
"p38" 0 -> 1 when "DUSP1"=1 and "MAP3K1_3"=1 and "TAK1"=1
"p38" 0 -> 1 when "DUSP1"=1 and "MAP3K1_3"=1 and "TAOK"=1
"p38" 1 -> 0 when "DUSP1"=0 and "MAP3K1_3"=0 and "MTK1"=0 and "TAK1"=0 and "TAOK"=0
"p38" 1 -> 0 when "DUSP1"=1 and "MAP3K1_3"=0 and "MTK1"=0 and "TAK1"=0
"p38" 1 -> 0 when "DUSP1"=1 and "MAP3K1_3"=0 and "MTK1"=0 and "TAOK"=0
"p38" 1 -> 0 when "DUSP1"=1 and "MAP3K1_3"=0 and "MTK1"=1 and "TAK1"=0 and "TAOK"=0
"p38" 1 -> 0 when "DUSP1"=1 and "MAP3K1_3"=1 and "MTK1"=0 and "TAK1"=0 and "TAOK"=0
"p53" 0 -> 1 when "ATM"=0 and "MDM2"=0 and "p38"=1
"p53" 0 -> 1 when "ATM"=1 and "MDM2"=0
"p53" 0 -> 1 when "ATM"=1 and "p38"=1
"p53" 1 -> 0 when "ATM"=0 and "MDM2"=1
"p53" 1 -> 0 when "ATM"=0 and "p38"=0
"p53" 1 -> 0 when "ATM"=1 and "MDM2"=1 and "p38"=0
"p70" 0 -> 1 when "ERK"=1 and "PDK1"=1
"p70" 1 -> 0 when "ERK"=0
"p70" 1 -> 0 when "PDK1"=0
initial_context "AKT"=0, "AP1"=0, "ATF2"=0, "ATM"=0, "Apoptosis"=0, "BCL2"=0, "CREB"=0, "DNA_damage"=0, "DUSP1"=0, "EGFR"=0, "EGFR_stimulus"=0, "ELK1"=0, "ERK"=0, "FGFR3"=0, "FGFR3_stimulus"=0, "FOS"=0, "FOXO3"=0, "FRS2"=0, "GAB1"=0, "GADD45"=0, "GRB2"=0, "Growth_Arrest"=0, "JNK"=0, "JUN"=0, "MAP3K1_3"=0, "MAX"=0, "MDM2"=0, "MEK1_2"=0, "MSK"=0, "MTK1"=0, "MYC"=0, "PDK1"=0, "PI3K"=0, "PKC"=0, "PLCG"=0, "PPP2CA"=0, "PTEN"=0, "Proliferation"=0, "RAF"=0, "RAS"=0, "RSK"=0, "SMAD"=0, "SOS"=0, "SPRY"=0, "TAK1"=0, "TAOK"=0, "TGFBR"=0, "TGFBR_stimulus"=0, "p14"=0, "p21"=0, "p38"=0, "p53"=0, "p70"=0