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Closes #34 function for growth parameters for height/length #45

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merged 22 commits into from
Jun 17, 2024

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zdz2101
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@zdz2101 zdz2101 commented May 30, 2024

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github-actions bot commented May 30, 2024

Code Coverage

Package Line Rate Health
admiralpeds 71%
Summary 71% (88 / 124)

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@zdz2101 i focused my review on the documentation and trust @kabis-ops and others to check the function code. and we can add more unit tests later as per the plan for the other function.

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@@ -93,14 +92,13 @@
#' advs <- dm_peds %>%
#' select(USUBJID, BRTHDTC, SEX) %>%
#' right_join(., vs_peds, by = "USUBJID") %>%
#' filter(USUBJID != "PEDS-1010") %>%
#' mutate(
#' VSDT = ymd(VSDTC),
#' BRTHDT = ymd(BRTHDTC)
#' ) %>%
#' derive_vars_duration(
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trunc_out = FALSE can be removed as its default anyway for this function - to simplify the example

@@ -93,14 +92,13 @@
#' advs <- dm_peds %>%
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can we add comments to this example please? as its quite a lot for users to follow with so much pre-processing before we even get to the example function call

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looks like I didn't push my comments... sorry for the delay

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#' The CDC/WHO growth chart metadata datasets are available in the package and will
#' require small modifications.
#' * `HEIGHT` - Height/Length
#' * `HEIGHTU` - Height Unit
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HEIGHTU - Height/Length Unit instead of only Height unit. I think that the name is confusing when length is selected

#' parameter = VSTESTCD == "WEIGHT",
#' analysis_var = VSSTRESN,
#' set_values_to_sds = exprs(
#' PARAMCD = "WTASDS",
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Should be PARAMCD = "WTHSDS"?

#' )
#'
#'
#' derive_params_growth_height(
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Where is patient 01-701-1033 gone ? While running this code I don't have any records created for patient 01-701-1033. Could you please clarify the reason ? thanks

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patient should be in there, at least showing on my end

#' right_join(., heights, by = c("USUBJID", "VSDTC"))
#'
#' advs_under2 <- advs %>%
#' filter(AGECUR_M <= 2)
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Why do you select patients under 2 months only ? should it not be 24 months to consider 2 years ?

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my mistake this was fixed

#' filter(AGECUR_M <= 2)
#'
#' advs_over2 <- advs %>%
#' filter(AGECUR_M > 2)
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Why do you select patients over 2 months only ? should it not be 24 months to consider 2 years ?

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see above

#' Derive Anthropometric indicators (Z-Scores/Percentiles-for-Age) based on Standard Growth Charts
#' for Weight/BMI/Head Circumference by Height/Length
#'
#' @param dataset Input dataset
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In the template we selected the records from the metadata where MEASURE ="LENGTH" for patients <730.5 days, and MEASURE="HEIGHT" for patients >=730.5 days. As Zelos mentioned, it will require additional variables to merge the right data depending on the age.
We also added message in the ADVS peds template for the same message("To derive height/length parameters, below function needs to call separately for Height and Length based on the input data and current age of the patient, as it depends on your CRF guidelines.").
I think it is easier to split it because if the user has only HEIGHT then there is only one call, similarly for LENGTH. But if the user has both LENGTH and HEIGHT in the data, it will complexify the merge. I think the user has more flexibility while splitting the derivation.

#' * `M` - Median
#' * `S` - Coefficient of variation
#'
#' @param parameter Anthropometric measurement parameter to calculate z-score or percentile

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Shall we include a reminder that the expected unit of weight is kg?

#'
#' The dataset can be derived from WHO or user-defined datasets.
#' The WHO growth chart metadata datasets are available in the package and will
#' require small modifications.

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The original WHO metadata table has height/length increment of 0.5, but the metadata in the admiralpeds packages has increment of 0.1. How was it extrapolated? Do we have any documentation on that?

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https://www.who.int/tools/child-growth-standards/standards/weight-for-length-height

scroll to the bottom on the expanded tables section you will find the increments were by 0.1

#' `HEIGHT_LENGTH`, `HEIGHT_LENGTHU`, `SEX`, `L`, `M`, `S`
#'
#' The dataset can be derived from WHO or user-defined datasets.
#' The WHO growth chart metadata datasets are available in the package and will
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Shall we list out the names of the metadata and clarify that "who_wt_for_lgth_boys" and "who_wt_for_lgth_girls" are for subjects with age <730.5 days, and "who_wt_for_ht_boys" and "who_wt_for_ht_girls" are for those with age>=730.5 days? By doing this, the user knows the metadata he/she can use, and also knows to apply different metadata based on subjects' age.

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This is a good idea, but I think we'll need to draw up a bigger vignette/article for metadata creation/preprocessing anyway

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hopefully the template and vignette can cover this more so user gets the full context

#' PARAMCD = "WTHPCTL",
#' PARAM = "Weight-for-height percentile"
#' )
#' )

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Shall we include codes to bind rows of advs_under2 and advs_over2?

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Makes sense just for the sake of completing the example

#' new_var_unit = AAGECURU,
#' start_date = BRTHDT,
#' end_date = VSDT,
#' out_unit = "months"

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In the ad_advs.R template (PR #32 ), the unit of age is days (with 730.5 days as cutoff). Shall we be consistent in the example here?

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Yes I will fix this

@Minlei0201
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Hi @zdz2101 , I've added a few comments on the PR (on the derive_params_growth_height.R). Feel free to take a look and let me know if you have any follow-up questions!

#' PARAM = "Weight-for-height z-score"
#' ),
#' set_values_to_pctl = exprs(
#' PARAMCD = "WTHPCTL",
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@zdz2101 please modify the PARAMCD to WGTHSDS/WGTHPCTL to be consistent with the ADVS template. Same changes are required for derive_params_by_age() function as well.
image
image

@@ -0,0 +1,41 @@
# derive_params_growth_heightlength ----

## Test 1: derive_params_growth_heightlength works ----
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Some outliers data to be added

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Additional testing will be handled in #50 #51

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Minor comments added

@rossfarrugia rossfarrugia merged commit a33f415 into main Jun 17, 2024
15 of 16 checks passed
@rossfarrugia rossfarrugia deleted the 34_new_func_lengthheight branch June 17, 2024 08:26
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New function: derive_params_growth_height - for BY LENGTH/HEIGHT growth parameters
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