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Definitive endoderm differentiation of human ESCs in G1 phase of the cell cycle

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Definitive endoderm differentiation of human embryonic stem cells in early G1 phase of the cell cycle

Source code of the manuscript:

Madrigal P, et al. Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation Nature Communications 2023

Processed data

All processed genome-wide datasets are publicly accessible in a genome browser at http://ngs.sanger.ac.uk/production/endoderm

A backup copy of the processed data files has been deposited in Zenodo (chip, atac, rna).

Gene expression data is also available at EMBL-EBI's resource Expression Atlas.

Raw data

Raw datasets are publicly available in the ArrayExpress collection of BioStudies.

E-MTAB-9124

E-MTAB-9194

E-MTAB-9276

Contact

For questions on the computational analysis: Pedro Madrigal. For questions on the experimental work: Siim Pauklin