-
Notifications
You must be signed in to change notification settings - Fork 7
Genetic interaction type flowchart
Kim Rutherford edited this page Dec 1, 2022
·
1 revision
flowchart TD;
A[Is the double<br>phenotype an inviable<br>cell population?];
A -->|Yes| C{{The single allele <br> phenotype should be a <br> viable cell population}};
C --> C2[Is the interacting<br>allele overexpressed?];
C2 -->|Yes| C2.1((Dosage<br>Lethality));
C2 -->|No| C2.2((Synthetic<br>Lethality));
A -->|No| D[Is the single<br>phenotype an inviable<br>cell population?];
D -->|Yes| E{{The double allele <br> phenotype should be a <br> viable cell population}};
E --> E2[Is the interacting<br>allele overexpressed?];
E2 -->|Yes| E2.1((Dosage<br>Rescue));
E2 -->|No| E2.2((Synthetic<br>Rescue));
D -->|No| F{{We have to know<br> if double is worse}};
F --> G[Is one of the<br>phenotypes a cell<br> population growth<br>phenotype?];
G -->|Yes| H{{The other phenotype<br> should be a population <br> growth phenotype too}};
H -->H2[Is the interacting<br>allele overexpressed?];
H2 -->|Yes| H2.1[double is <br>worse?];
H2.1 -->|Yes| H2.1.1((Dosage<br>Growth<br>Defect));
H2.1 -->|No| H2.1.2((Dosage<br>Rescue));
H2 -->|No| H2.2[double is <br>worse?];
H2.2 -->|Yes| H2.2.1((Synthetic<br>Growth<br>Defect));
H2.2 -->|No| H2.2.2((Synthetic<br>Rescue));
G -->|No| I[double is <br>worse?];
I -->|Yes| J((Phenotypic<br>Enhancement));
I -->|No| K((Phenotypic<br>Suppresion));