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term move and rename, possible #2927

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ValWood opened this issue Dec 12, 2016 · 10 comments
Open

term move and rename, possible #2927

ValWood opened this issue Dec 12, 2016 · 10 comments
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@ValWood
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ValWood commented Dec 12, 2016

I was about to request a new child of

FYPO:0002423 inviable after spore germination, without cell division, septated cells with abnormal cell shape
(stub)

inviable after spore germination, without cell division, multi-septated cells swollen elongated cells
but I was pretty sure this phenotype existed already

its this:
rubber glove

Sorbitol partially rescued sbg1Δ cells and sbg1Δ cells germinated on media with sorbitol survived for up to 3 days. However, cytokinesis still failed and cell
morphology was defective in these cells, which were elongated, multi-septated, and swollen (Fig 1B and S2 Movie).

However, since I was looking at these earlier, I remembered we had described this slightly differently in cell cycle/morphology paper.

It's
inviable after spore germination, without cell division, with swollen, branched, elongated germ tube

With the branched,
FYPO:0002515
FYPO:0003005
we can assume they are also septated (the branching in this context is a result of incorrect cytokinesis but the cells are septated (often multispetate).

(Jacky -this is rubber glove phenotype!)

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@ValWood
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ValWood commented Dec 18, 2016

I'm pretty sure we do need to do this.

rename the existing term to include "multi-septate" and elongated not just septated

@ValWood
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ValWood commented Dec 18, 2016

see also pombase/curation#1219

note to self PMID:27898700

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@ValWood
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ValWood commented Dec 19, 2016

So existing term

"FYPO:0002423 inviable after spore germination, without cell division, septated cells with abnormal cell shape"

Jacky, the existing annotations to this term from the deletion project are these:
http://www.pombase.org/spombe/related/FYPO:0002515
(I think bgs1 was rubber glove phenotype...do you have a picture?)

These phenotypes (based on the one above) appear to be also both "multiseptated and elongated" (they don't look like traditional elongated cells , because the defect is separation.

The look a bit like one of those long balloons that has been made into "sausages".
Although now I am wondering, are these still a single cell, or are they really multiple cells chained together...it seems like the latter. so....we say that these cells have no division, but it looks as though they divide, but do not fully separate....

SPBP22H7.03 is just published as sbg1

So I'm not sure either.....I have stuggled with these cell separation mutants before.... I have a folder with questions and examples.......

@ValWood
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ValWood commented Dec 19, 2016

maybe its really this?
http://www.pombase.org/spombe/related/FYPO:0001971

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mah11 commented Dec 11, 2019

anything to do for this one?

@ValWood
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ValWood commented Dec 11, 2019

I will take this. I would like to check what this phenotype is annotated top.

@ValWood ValWood self-assigned this Dec 11, 2019
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