#smallAnimalMRgHIFU

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Open-source plans for constructing and implementing a preclinical MRgHIFU/MRgFUS system on a small-animal MRI scanner.

DOI: 10.5281/zenodo.51633

ME Poorman, VL Chaplin, K Wilkens, MD Dockery, T Giorgio, WA Grissom, and CF Caskey

Vanderbilt University Institue for Imaging Science

Freely available for use and modification with citation of original distribution/article (https://jtultrasound.biomedcentral.com/articles/10.1186/s40349-016-0066-7). See license file for more information.

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MRgFUS_software:

• Matlab code to control sonication real-time with baseline subtraction thermometry and a PID feedback controller
• V1: Single script version - intended for debugging purposes only
• V2: Modular software and GUI commented and tested - intended for use and straightforward modification
• ARFI folder: pulse sequence and recon code. C code must be compiled prior to use
• calcCEM_vect.m: computes thermal dose given focal temperature
• initFGEN.m: initializes waveform generator
• offFGEN.m: stops all waveform outputs to transducer
• parsepp.m: reads parameter file
• pidUpdate.m: PID controller computation
• readInFID.m: reads in next image from .fid data file
• runControlSoftware.m: master script, contains GUI to set up execution, begins sonication
• runExpGui.m/.fig: button to begin sonication
• runTempRecon.m: computes thermometry, calls other modules for execution
• userinterface.m/fig: optional GUI to set up sonication parameters

###MRgHIFU_hardware_pt#:

• Solidworks files and parts list of all hardware components used to build the system
• Split into 4 ".zip" files to comply with size requirements. Unzip into same folder for proper use.

Instructions for use:

• See instructions file

License

• See license file

Helpful tips:

• On the Varian systems, the current acquisition file can be found in '~/vnmrsys/exp2/acqfil/fid'
• Previously stored Varian data is found in'~/vnmrsys/data/studies/s_YYYYMMDD_##'
• Can run software in recon mode to see past execution