XS is a skilled FASTQ read simulation tool, flexible, portable (does not need a reference sequence) and tunable in terms of sequence complexity. XS handles Ion Torrent, Roche-454, Illumina and ABI-SOLiD simulation sequencing types. It has several running modes, depending on the time and memory available, and is aimed at testing computing infrastructures, namely cloud computing of large-scale projects, and testing FASTQ compression algorithms. Moreover, XS offers the possibility of simulating the three main FASTQ components individually (headers, DNA sequences and quality-scores). Quality-scores can be simulated using uniform and Gaussian distributions.
git clone https://github.com/pratas/XS.git
./XS [parameters] [outFile]
To see the possible options type
On using this software please cite:
Pratas, D., Pinho, A. J., & Rodrigues, J. M. R. (2014). XS: a FASTQ read simulator. BMC research notes, 7(1), 40.
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