skippy is a 80-bit key, 32-bit block cipher based on Skipjack. The Python code for the algorithm is a direct translation from C to Python of skip32.c by Greg Rose.
>>> import skippy
>>> key = b"s3cr3t_k3y"
>>> cipher = skippy.Skippy(key)
>>> encrypted = cipher.encrypt(42)
>>> encrypted
1139197039
>>> decrypted = cipher.decrypt(encrypted)
>>> decrypted
42skippy is free and unencumbered public domain software. For more information, see http://unlicense.org/ or the accompanying UNLICENSE file.