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2021 (421)
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#. Abbatemarco, S. et al. (2021). PQN-59 and GTBP-1 contribute to stress granule formation but are not essential for their assembly in *C. elegans* embryos. **Journal of Cell Science**. https://doi.org/10.1242/jcs.258834 ๐Ÿ“—
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#. Almeida, C. F. et al. (2021). Satellite cells deficiency and defective regeneration in dynamin 2โ€related centronuclear myopathy. **The FASEB Journal**. https://doi.org/10.1096/fj.202001313RRR ๐Ÿ“—

#. Alves, R. et al. (2021). Correlation Tensor MRI deciphers underlying kurtosis sources in stroke. **NeuroImage**. https://doi.org/10.1016/j.neuroimage.2021.118833 ๐Ÿ˜ž

#. Alzghool, O. M. et al. (2021). (S)-[\ :sup:`18`\ F]THK5117 brain uptake is associated with Aฮฒ plaques and MAO-B enzyme in a mouse model of Alzheimerโ€™s disease. **Neuropharmacology**. https://doi.org/10.1016/j.neuropharm.2021.108676 ๐Ÿ“—

#. Amarilla, A. A. et al. (2021). A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses. **Nature Communications**. https://doi.org/10.1038/s41467-021-23779-5 ๐Ÿ“—
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#. Bhagavatula, S. et al. (2021). A Miniaturized Platform for Multiplexed Drug Response Imaging in Live Tumors. **Cancers**. https://doi.org/10.3390/cancers13040653 ๐Ÿ“—

#. Bhattacharjee, S. et al. (2021). Cluster Analysis of Cell Nuclei in H&E-Stained Histological Sections of Prostate Cancer and Classification Based on Traditional and Modern Artificial Intelligence Techniques. **Diagnostics**. https://doi.org/10.3390/diagnostics12010015 ๐Ÿ˜ž

#. Bleeser, T. et al. (2021). Effects of Maternal Abdominal Surgery on Fetal Brain Development in the Rabbit Model. **Fetal Diganosis and Therapy**. https://doi.org/10.1159/000512489 ๐Ÿ“—

#. Blocker, S. J. et al. (2021). Ex Vivo MR Histology and Cytometric Feature Mapping Connect Three-dimensional in Vivo MR Images to Two-dimensional Histopathologic Images of Murine Sarcomas. **Radiology: Imaging Cancer**. https://doi.org/10.1148/rycan.2021200103 ๐Ÿ“—

#. Boby, N. et al. (2021). Protective Effect of Pyrus ussuriensis Maxim. Extract against Ethanol-Induced Gastritis in Rats. **Antioxidants**. https://doi.org/10.3390/antiox10030439 ๐Ÿ˜ž

#. Bochem, J. et al. (2021). Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy. **Journal for ImmunoTherapy of Cancer**. https://doi.org/10.1136/jitc-2021-003439 ๐Ÿ“—

#. Boothby, I. C. et al. (2021). Early-life inflammation primes a T helper 2 cellโ€“fibroblast niche in skin. **Nature**. https://doi.org/10.1038/s41586-021-04044-7 ๐Ÿ“—

#. Bortolotti, D. et al. (2021). Late-onset intrauterine growth restriction and HHV-6 infection: A pilot study. **Journal of Medical Virology**. https://doi.org/10.1002/jmv.27138 ๐Ÿ˜ž
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#. Foersch, S. et al. (2021). Deep learning for diagnosis and survival prediction in soft tissue sarcoma. **Annals of Oncology**. https://doi.org/10.1016/j.annonc.2021.06.007 ๐Ÿ“—

#. Franceschini, N. et al. (2021). A murine mesenchymal stem cell model for initiating events in osteosarcomagenesis points to CDK4/CDK6 inhibition as a therapeutic target. **Laboratory Investigation**. https://doi.org/10.1038/s41374-021-00709-z ๐Ÿ“—

#. Friedrich, M. et al. (2021). Intrathecal activation of CD8\ :sup:`+` memory T cells in IgG4-related disease of the brain parenchyma. **EMBO Molecular Medicine**. https://doi.org/10.15252/emmm.202113953 ๐Ÿ˜ž

#. Fujii, T. et al. (2021). MEF2C regulates osteoclastogenesis and pathologic bone resorption via c-FOS. **Bone Research**. https://doi.org/10.1038/s41413-020-00120-2 ๐Ÿ˜ž
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#. Kamata, T. et al. (2021). Statins mediate anti- and pro-tumourigenic functions in lung adenocarcinoma development by remodelling the tumour microenvironment . **Disease Models & Mechanisms**. https://doi.org/10.1242/dmm.049148 ๐Ÿ“—

#. Kandefors, M. et al. (2021). CD105+CD90+CD13+ identifies a clonogenic subset of adventitial lung fibroblasts. **Scientific Reports**. https://doi.org/10.1038/s41598-021-03963-9 ๐Ÿ˜ž

#. Kang, Y. et al. (2021). Large, Anionic Liposomes Enable Targeted Intraperitoneal Delivery of a TLR 7/8 Agonist To Repolarize Ovarian Tumorsโ€™ Microenvironment. **Bioconjugate Chemistry**. https://doi.org/10.1021/acs.bioconjchem.1c00139 ๐Ÿ“—

#. Karnell, J. L. et al. (2021). Depleting plasmacytoid dendritic cells reduces local type I interferon responses and disease activity in patients with cutaneous lupus. **Science Translational Medicine**. https://doi.org/10.1126/scitranslmed.abf8442 ๐Ÿ˜ž
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#. Kwon, J-T. et al. (2021). An amygdala circuit that suppresses social engagement. **Nature**. https://doi.org/10.1038/s41586-021-03413-6 ๐Ÿ“—

#. Kรผrten, C. H. L. et al. (2021). Investigating immune and non-immune cell interactions in head and neck tumors by single-cell RNA sequencing. **Nature Communications**. https://doi.org/10.1038/s41467-021-27619-4 ๐Ÿ“—

#. Labadie, K. P. et al. (2021). Glypican-3 targeted delivery of :sup:`89`\ Zr and :sup:`90`\ Y as a theranostic radionuclide platform for hepatocellular carcinoma. **Scientific Reports**. https://doi.org/10.1038/s41598-021-82172-w ๐Ÿ˜ž

#. Lamont, L. et al. (2021). Quantitative mass spectrometry imaging of drugs and metabolites: a multiplatform comparison. **Analytical and Bioanalytical Chemistry**. https://doi.org/10.1007/s00216-021-03210-0 ๐Ÿ˜ž
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#. Li, T. et al. (2021). Endometrial laminin subunit beta-3 expression associates with reproductive outcome in patients with repeated implantation failure. **Journal of Assisted Reproduction and Genetics**. https://doi.org/10.1007/s10815-021-02135-y ๐Ÿ“—

#. Li, X. et al. (2021). Deep learning segmentation of glomeruli on kidney donor frozen sections. **Journal of Medical Imaging**. https://doi.org/10.1117/1.JMI.8.6.067501 ๐Ÿ˜ž

#. Li, Z. et al. (2021). Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen. **Nature Communications**. https://doi.org/10.1038/s41467-021-26530-2 ๐Ÿ˜ž

#. Lin, T.-Y. et al. (2021). Fibroblast dedifferentiation as a determinant of successful regeneration. **Developmental Cell**. https://doi.org/10.1016/j.devcel.2021.04.016 ๐Ÿ“—
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#. Quaas, A. et al. (2021). Sex-specific prognostic effect of CD66b-positive tumor-infiltrating neutrophils (TANs) in gastric and esophageal adenocarcinoma. **Gastric Cancer**. https://doi.org/10.1007/s10120-021-01197-2 ๐Ÿ“—

#. Quesada-Masachs, E. et al. (2021). Upregulation of HLA class II in pancreatic beta cells from organ donors with type 1 diabetes. **Diabetologia**. https://doi.org/10.1007/s00125-021-05619-9 ๐Ÿ“—

#. Rajakumar, S. A. et al. (2021). Targeted blockade of immune mechanisms inhibit B precursor acute lymphoblastic leukemia cell invasion of the central nervous system. **Cell Reports Medicine**. https://doi.org/10.1016/j.xcrm.2021.100470 ๐Ÿ“—

#. Rajendran, S. et al. (2021). IL-17 is expressed on beta and alpha cells of donors with type 1 and type 2 diabetes. **Journal of Autoimmunity**. https://doi.org/10.1016/j.jaut.2021.102708 ๐Ÿ“—

#. Rakaee, M. et al. (2021). Tertiary lymphoid structure score: a promising approach to refine the TNM staging in resected non-small cell lung cancer. **British Journal of Cancer**. https://doi.org/10.1038/s41416-021-01307-y ๐Ÿ˜ž
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#. Siegert, E. et al. (2021). Systemic sclerosis-associated myositis features minimal inflammation and characteristic capillary pathology. **Acta Neuropathologica**. https://doi.org/10.1007/s00401-021-02305-3 ๐Ÿ“—

#. Sievers, C. et al. (2021). Comprehensive multiomic characterization of human papillomavirus-driven recurrent respiratory papillomatosis reveals distinct molecular subtypes. **Nature Communications**. https://doi.org/10.1038/s42003-021-02942-0 ๐Ÿ˜ž

#. Sikic, D. et al. (2021). Utility of stromal tumor infiltrating lymphocyte scoring (sTILs) for risk stratification of patients with muscle-invasive urothelial bladder cancer after radical cystectomy. **Urologic Oncology: Seminars and Original Investigations**. https://doi.org/10.1016/j.urolonc.2021.07.025 ๐Ÿ“—

#. Silva, B. A. et al. (2021). A thalamo-amygdalar circuit underlying the extinction of remote fear memories. **Nature Neuroscience**. https://doi.org/10.1038/s41593-021-00856-y ๐Ÿ“—
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#. Sonntag, T. et al. (2021). Distribution of Gold Nanoparticles in the Anterior Chamber of the Eye after Intracameral Injection for Glaucoma Therapy. **Pharmaceutics**. https://doi.org/10.3390/pharmaceutics13060901 ๐Ÿ˜ž

#. Soria, X. et al. (2021). BRAFV600E Mutant Allele Frequency (MAF) Influences Melanoma Clinicopathologic Characteristics. **Cancers**. https://doi.org/10.3390/cancers13205073 ๐Ÿ“—

#. Spiljar, M. et al. (2021). Cold exposure protects from neuroinflammation through immunologic reprogramming. **Cell Metabolism**. https://doi.org/10.1016/j.cmet.2021.10.002 ๐Ÿ˜ž

#. Stenvall, C-G. A. et al. (2021). Targeted deletion of keratin 8 in intestinal epithelial cells disrupts tissue integrity and predisposes to tumorigenesis in the colon. **Cellular and Molecular Life Sciences**. https://doi.org/10.1007/s00018-021-04081-5 ๐Ÿ“—

#. Stockton, J. D. et al. (2021). Complete response to neoadjuvant chemoradiotherapy in rectal cancer is associated with RAS/AKT mutations and high tumour mutational burden. **Radiation Oncology**. https://doi.org/10.1186/s13014-021-01853-y ๐Ÿ“—

#. Strait, A. A. et al. (2021). Distinct immune microenvironment profiles of therapeutic responders emerge in combined TGFฮฒ/PD-L1 blockade-treated squamous cell carcinoma. **Communications Biology**. https://doi.org/10.1038/s42003-021-02522-2 ๐Ÿ“—
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#. Valencia, K. et al. (2021). Two alternative cell line models for the study of multiorganic metastasis and immunotherapy in Lung Squamous Cell Carcinoma. **Disease Models & Mechanisms**. https://doi.org/10.1242/dmm.049137 ๐Ÿ“—

#. Valentijn, F. A. et al. (2021). CCN2 Aggravates the Immediate Oxidative Stressโ€“DNA Damage Response following Renal Ischemiaโ€“Reperfusion Injury. **Antioxidants**. https://doi.org/10.3390/antiox10122020 ๐Ÿ“—

#. Van Hove, L. et al. (2021). Fibrotic enzymes modulate woundโ€induced skin tumorigenesis. **EMBO Reports**. https://doi.org/10.15252/embr.202051573 ๐Ÿ˜ž

#. Van Neerven, S. M. et al. (2021). _Apc_-mutant cells act as supercompetitors in intestinal tumour initiation. **Nature**. https://doi.org/10.1038/s41586-021-03558-4 ๐Ÿ“—
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#. Zacarรญas-Fluck, M. F. et al. (2021). The Wnt signaling receptor Fzd9 is essential for Myc-driven tumorigenesis in pancreatic islets. **Life Science Alliance**. https://doi.org/10.26508/lsa.201900490 ๐Ÿ“—

#. Zawadzki, P. et al. (2021). The Microorganism Detection System (SDM) for microbiological control of cosmetic products. **Annals of Agricultural and Environmental Medicine**. https://doi.org/10.26444/aaem/144668 ๐Ÿ“—

#. Zerdes, I. et al. (2021). Interplay between copy number alterations and immune profiles in the early breast cancer Scandinavian Breast Group 2004-1 randomized phase II trial: results from a feasibility study. **npj Breast Cancer**. https://doi.org/10.1038/s41523-021-00352-3 ๐Ÿ“—

#. Zhang, N. et al. (2021). Electrophysiologic and Morphologic Strain Differences in a Low-Dose NaIO3-Induced Retinal Pigment Epithelium Damage Model. **Translational Vision Science & Technology**. https://doi.org/10.1167/tvst.10.8.10 ๐Ÿ“—

#. Zhang, Q. et al. (2021). A human orthogonal IL-2 and IL-2Rฮฒ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemia. **Science Translational Medicine**. https://doi.org/10.1126/scitranslmed.abg6986 ๐Ÿ˜ž

#. Zhang, Y. et al. (2021). Patch test relevant concentrations of metal salts cause localized cytotoxicity, including apoptosis, in skin *ex vivo*. **Contact Dermatitis**. https://doi.org/10.1111/cod.13940 ๐Ÿ˜ž

#. Zhao, P. et al. (2021). Efficacy of AAV9-mediated SGPL1 gene transfer in a mouse model of S1P lyase insufficiency syndrome. **JCI Insight**. https://doi.org/10.1172/jci.insight.145936 ๐Ÿ˜ž
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#. Zhou, J. et al. (2021). Orphan nuclear receptor TLX promotes immunosuppression via its transcriptional activation of PD-L1 in glioma. **Journal for ImmunoTherapy of Cancer**. http://dx.doi.org/10.1136/jitc-2020-001937 ๐Ÿ˜ž

#. Zindel, J. et al. (2021). Intraperitoneal microbial contamination drives post-surgical peritoneal adhesions by mesothelial EGFR-signaling. **Nature Communications**. https://doi.org/10.1038/s41467-021-27612-x ๐Ÿ“—

#. Zoupi, L. et al. (2021). Selective vulnerability of inhibitory networks in multiple sclerosis. **Acta Neuropathologica**. https://doi.org/10.1007/s00401-020-02258-z ๐Ÿ“—

#. van Neeren, S. M. et al. (2021). _Apc_-mutant cells act as supercompetitors in intestinal tumour initiation. **Nature**. https://doi.org/10.1038/s41586-021-03558-4 ๐Ÿ“—
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