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In [11]: Chem.CanonSmiles('C[N@]1C[C@@](F)(Cl)C1')
Out[11]: 'C[N@]1C[C@@](F)(Cl)C1'
In [12]: Chem.CanonSmiles('C[N@]1O[C@@](F)(Cl)C1')
Out[12]: 'CN1C[C@](F)(Cl)O1'
That three-coordinate N shouldn't be a chiral center. The stereochem is correctly removed when it's "normal" chirality, but it persists when ring stereo is involved (the first example).
The reason this happens is that the logic which allows ring stereo essentially passes all atoms through, even those which aren't allowed to have atomic chirality (like these Ns).
The text was updated successfully, but these errors were encountered:
Here's the reproducible:
That three-coordinate N shouldn't be a chiral center. The stereochem is correctly removed when it's "normal" chirality, but it persists when ring stereo is involved (the first example).
The reason this happens is that the logic which allows ring stereo essentially passes all atoms through, even those which aren't allowed to have atomic chirality (like these Ns).
The text was updated successfully, but these errors were encountered: