Pleiotropic effects from rare coding variants in schizophrenia and NDDs

R code used for research presented in Rees et al. ‘Schizophrenia, Autism Spectrum Disorders and Developmental Disorders Share Specific Disruptive Coding Mutations’. BioRxiv, 4 September 2020, 2020.09.02.279265. https://doi.org/10.1101/2020.09.02.279265.

code

Contains R markdown and R scripts for main analyses.

Genic_pleiotropy_main_analysis.Rmd produces results presented in Table 1

Genic_pleiotropy_poisson_analysis.Rmd produces results presented in SM Table S1/2

Allelic_pleiotropy_main_analysis.Rmd produces results presented in Table 3

data

Contains input data used by R scripts

output

Contains results tables created by R scripts