This project is a Julia 1.6.0 replication of Lipsitch et al (1996), a paper in evolutionary modelling that challenged notions on the dynamics of viral transmission. Full reference to the original article:
M. Lipsitch, S. Siller, and M. A. Nowak. “THE EVOLUTION OF VIRULENCE IN PATHOGENS WITH VERTICAL ANDHORIZONTAL TRANSMISSION.” In:Evolution50.5 (1996), pp. 1729–1741. eprint:https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1558-5646.1996.tb03560.x.
The goal of this project was to replicate the epidemiological model for the evolution of virulence presenting trade-offs between horizontal and vertical transmission of pathogens.
The original article can be found in the file "Lipsitch_1996.pdf".
Julia Lang scripts defining model parameters (as found in the original study) are available in the folder "Model_scripts".
All figures produced in the replication study are found in their respective folders.
To run our replication code, clone our repository to your computer, checkout to the master branch, and run the following lines:
] activate .
] instantiateFinally, run the 00run_project.jl file in the Model_scripts/ folder.