We created a cycle visualizer to help hospital and or public health officials graph and find optimal antibiotic cycles to use for their specific area.
Users are able to input data as a susceptibility/resistance matrix of antibiotics and calculate and graph ideal antibiotic cycles.
References:
Imamovic L, et al. (2018) Drug-Driven Phenotypic Convergence Supports Rational Treatment Strategies of Chronic Infections. Cell. 2018 Jan 11;172(1-2):121-134.e14. doi: 10.1016/j.cell.2017.12.012. Epub 2018 Jan 4
Imamovic L, et al. (2013) Use of collateral sensitivity networks to design drug cycling protocols that avoid resistance development. Sci Transl Med. 2013 Sep 25;5(204):204ra132. doi: 10.1126/scitranslmed.3006609.