Sublineage of KP.2 (FLiRT) with S:Q1201K ( 6 sequences , 5 countries, 4 continents 0,5% samples collected worlwide in March)

[FedeGueli]

i just noticed that fast growing KP.2 lineage has got also S:Q1201K (C25163A) ,
this mutation is a one nuc mutation but it is usually accompanied by a silent mutation in the S:1200 Codon : (C25162A).
This combination is not new and has been spotted and discussed first by @ryhisner since 2023 or even before.
While this mutation has not suceeded in become fixated in circualting viruses , this time popped up in the fastest lineage on earth (apparently and as of today) KP.2 .
All the 4 samples of KP.2 with this mutation have been collected in March scoring a 4/893 globally.
More interestingly these samples come from 4 countries dislocated in 3 continents.
Hence i propose it immediately.
Nextclade screening of the double nuc mutation:

Defining mutations: KP.2 > C25162A, S:Q1201K (C25163A)
Query: C25162A, C25163A, T3565C,G22599C
Samples: 4
Countries: England, US (California), India (via GBW), Canada
IDs: EPI_ISL_18974372, EPI_ISL_18975453, EPI_ISL_18980156,
EPI_ISL_18983461
Tree:


https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_35acd_44e770.json?c=gt-nuc_22599,22928,7113,3565&gmax=23928&gmin=2565&label=id:node_6943906

[aviczhl2]

+1 GBW from Brazil
+1 GBW-H10, country unknown(not the same as other GBWs as it is collected on 3-7 and sampled in NJ)

[FedeGueli]

+1 GBW from Brazil +1 GBW-H10, country unknown(not the same as other GBWs as it is collected on 3-7 and sampled in NJ)

Thank you it seems exploding , lets see if more samples will come in

[aviczhl2]

Designated KP.2.1 via cov-lineages/pango-designation@1da2694