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XBB.1.5.70 (455-456) sublineage with S:V511I already internationally spread.(17 seqs 9 countries) #300

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FedeGueli opened this issue Jul 1, 2023 · 5 comments
Closed

XBB.1.5.70 (455-456) sublineage with S:V511I already internationally spread.(17 seqs 9 countries) #300

FedeGueli opened this issue Jul 1, 2023 · 5 comments
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Convergent evolution Lineages with convergent mutations designated
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GK.2

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@FedeGueli
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FedeGueli commented Jul 1, 2023 •
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Gisaid query: T2824C ,G23093A

Samples: 13
EPI_ISL_17737583, EPI_ISL_17737585, EPI_ISL_17782370,
EPI_ISL_17782389, EPI_ISL_17790041, EPI_ISL_17792496,
EPI_ISL_17804459, EPI_ISL_17831187, EPI_ISL_17859383,
EPI_ISL_17872016, EPI_ISL_17881008, EPI_ISL_17881100,

Countries: 9
US, Austria, Iceland, Italy, France, Canada , Switzerland,Spain, Japan (edited)

Tree:
Schermata 2023-07-02 alle 00 58 39
Schermata 2023-07-02 alle 00 58 56

Updated with new samples (04/07)
Schermata 2023-07-05 alle 20 01 31

https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_2a097_5afc10.json?label=id:node_6905156

Defining mutations:
XBB.1.5.70 >>> C7564T, Orf1a:A4068S (G12467T = NSP8_A126S) > C23741T > T2824C, S:V511I (G23093A)

To be noticed that S:V511I is the defining of XBB.1.5.71 that seems doing well in Spain and represents 50+% of the samples carrying this mutation since the start of the pandemic.

Ping @corneliusroemer
@FedeGueli FedeGueli added Rapid review needed Convergent evolution Lineages with convergent mutations labels Jul 1, 2023
@FedeGueli FedeGueli changed the title XBB.1.5.70 (455-456) sublineage with S:V511I already internationally spread.(12 seqs 7 countries) XBB.1.5.70 (455-456) sublineage with S:V511I already internationally spread.(13 seqs 8 countries) Jul 3, 2023
@FedeGueli
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One more coming from Spain

@FedeGueli FedeGueli changed the title XBB.1.5.70 (455-456) sublineage with S:V511I already internationally spread.(13 seqs 8 countries) XBB.1.5.70 (455-456) sublineage with S:V511I already internationally spread.(17 seqs 9 countries) Jul 5, 2023
@FedeGueli
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FedeGueli commented Jul 5, 2023 •
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4 new samples one new country (japan) It seems fast
ping @corneliusroemer

@FedeGueli
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Designated GK.2

FedeGueli referenced this issue in cov-lineages/pango-designation Jul 10, 2023
@corneliusroemer
Designate GK.2 (XBB.1.5.70.2, S:V511I) with 20 seqs
5780e06
@aviczhl2
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Shall add milestone for this

@FedeGueli FedeGueli added this to the GK.2 milestone Aug 27, 2023
@FedeGueli
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Thank you @aviczhl2

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