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[FEATURE] Cluster junctions by hierarchical clustering #54

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Irallia opened this issue Feb 10, 2021 · 0 comments · Fixed by #99
Closed

[FEATURE] Cluster junctions by hierarchical clustering #54

Irallia opened this issue Feb 10, 2021 · 0 comments · Fixed by #99
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@Irallia
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Irallia commented Feb 10, 2021

Hierarchical clustering is the clustering method employed by SVIM. It will be implemented in src/modules/clustering/hierarchical_clustering_method.cpp.

Steps:

  1. Generate partitions of junctions lying close to each other on the reference genome (clustering is O(n^2) so it's much faster on a small partition than the entire genome)
  2. Cluster the junctions in each partition using agglomerative hierarchical clustering

We could use https://github.com/cdalitz/hclust-cpp as an existing implementation for the 2nd step.

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