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Welcome to MotifScan

Github Actions Documentation Status PyPI Python Version Bioconda Codecov License

MotifScan

Scan input genomic regions with known DNA motifs

Given a set of input genomic regions, MotifScan scans the sequences to detect the occurrences of known motifs. It can also applies a statistical test on each motif to check whether the motif is significantly over- or under-represented (enriched or depleted) in the input genomic regions compared to another set of control regions.

Workflow

image/MotifScan.png

Citation

Sun, H., Wang, J., Gong, Z. et al. Quantitative integration of epigenomic variation and transcription factor binding using MAmotif toolkit identifies an important role of IRF2 as transcription activator at gene promoters. Cell Discov 4, 38 (2018).

Contents

.. toctree::
   :maxdepth: 1

   Home<self>
   install
   quickstart
   userguide
   changelog
   faq
   help
   license


The MotifScan package is developed by ShaoLab at CAS-MPG Partner Institute for Computational Biology, SIBS, CAS.

.. seealso::
   GitHub repository of MotifScan: https://github.com/shao-lab/MotifScan