Homologous Recombination Deficiency Unrelated to Platinum and PARP Inhibitor Response in Cell Line Libraries

This page provides data and code to reproduce the results of the corresponding paper.

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Analysis environments

Python 3.8.15

• pandas 1.3.4
• numpy 1.20.3
• matplotlib 3.4.3
• seaborn 0.11.2
• scipy 1.7.2

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Contents

data

• Integrated genomic profiles of cancer cell lines
• Processed drug response AUC values and category annotations

download

• Information on the original datasets for drug response AUC values and category annotations

scripts

• step1 drug annotation and drug auc integration
• step2 analysis

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Citation

Scientific data 2024 Feb 6;11(1):171
Homologous Recombination Deficiency Unrelated to Platinum and PARP Inhibitor Response in Cell Line Libraries
Shiro Takamatsu, Kosuke Murakami, Noriomi Matsumura
PMID: 38321018, PMCID: PMC10847511
DOI: 10.1038/s41597-024-03018-4