This is a very simple app (based on one of the Jersey examples), which reproduces the issue with jersey2-guice and Jersey >= 2.16 packed into the uber-jar (Squarespace/jersey2-guice#30).

To run:

$ mvn clean package
$ java -jar target/jersey-guice-issue-1.0-SNAPSHOT.jar

To solve the issue, uncomment string in pom.xml in maven-shade-plugin configuration.