Learning Objectives # BTEC-620-Spring2024 4 Credits Fundamentals of Bioinformatics Bioinformatics (topics including sequence alignment algorithms, scoring matrices, microarray analysis, phylogenetic analysis, bootstrapping, tree building, secondary & tertiary structure prediction, homology modeling, and protein folding)], visualization: heat maps, volcano plots, pie charts, Sequence alignments (Margaret Dayhoff, PAM, blossom scoring matrices, global & local alignment).Gene Expression Omnibus (GEO) datasets mining, Microarray data analysis: Read, Pre-processing/Normalization (Affy, Oligo, Limma-RMA, Quantile, Mas5.0), Visualization: Heat maps, box plots, Fold change expression analysis, Gene Set Enrichment Analysis (GSEA), Pathways and protein downstream interactome analysis. Youtube Teaching Channel:

Bioinformatics: Bioinformatics: Bioinformatics: Bioinformatics: Bioinformatics: Bioinformatics: Bioinformatics: Bioinformatics: Bioinformatics:

Phylogenetic Analysis: https://github.com/spawar2/BTEC-620-Spring-2023/blob/main/Phylogenetic-Analysis.R Link Blast, Sequence alignments (Margaret Dayhoff, PAM, Blossom scoring matrices, global & local alignment): https://youtu.be/Lx1jkr3UKwA BIOL620-Spring-2024 (4 credit) (2 students) *Graduate Class (Masters & Ph.D. Level) https://campuspress.yale.edu/shrikantpawar/files/2024/05/Student-Evaluations-2021-2024-3df60a3eaf357f31.pdf https://www.claflin.edu/ Claflin University, Orangeburg, South Carolina, USA