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#!/usr/bin/env python | ||
"""Test GOEnrichmentStudy::print_results.""" | ||
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import os | ||
import sys | ||
from goatools.test_data.genes_NCBI_10090_ProteinCoding import GENEID2NT as GeneID2nt_mus | ||
from goatools.test_data.nature3102_goea import get_geneid2symbol, get_goeaobj | ||
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__copyright__ = "Copyright (C) 2016-2017, DV Klopfenstein, H Tang, All rights reserved." | ||
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REPO = os.path.join(os.path.dirname(os.path.abspath(__file__)), "../") | ||
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def test_example(): | ||
"""Test writing GOEA results into a tab-separated file.""" | ||
# -------------------------------------------------------------------- | ||
# -------------------------------------------------------------------- | ||
# Gene Ontology Enrichment Analysis (GOEA) | ||
# -------------------------------------------------------------------- | ||
# -------------------------------------------------------------------- | ||
fout_tsv = os.path.join(REPO, 'goea_results.tsv') | ||
taxid = 10090 # Mouse study | ||
# Load ontologies, associations, and population ids | ||
geneids_pop = GeneID2nt_mus.keys() | ||
geneids2symbol_study = get_geneid2symbol("nbt.3102-S4_GeneIDs.xlsx") | ||
geneids_study = geneids2symbol_study.keys() | ||
goeaobj = get_goeaobj("fdr_bh", geneids_pop, taxid) | ||
# Run GOEA on study | ||
goea_results_all = goeaobj.run_study(geneids_study) | ||
goea_results_sig = [r for r in goea_results_all if r.p_fdr_bh < 0.05] | ||
goeaobj.wr_tsv(fout_tsv, goea_results_sig) | ||
assert os.path.exists(fout_tsv) | ||
goeaobj.prt_tsv(sys.stdout, goea_results_sig) | ||
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if __name__ == '__main__': | ||
test_example() | ||
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# Copyright (C) 2016-2017, DV Klopfenstein, H Tang, All rights reserved. |