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receptor_a and receptor_b are the same True/False #122

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Lijinluu opened this issue Sep 17, 2019 · 5 comments
Closed

receptor_a and receptor_b are the same True/False #122

Lijinluu opened this issue Sep 17, 2019 · 5 comments

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@Lijinluu
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Hi,thanks for your great database and tool . When i was using the cellphonedb to predict functional interactions, I found some interacting_pair have the same annotation (True True or False False ) at receptor_a and receptor_b column in significant_means.txt file.

Just like that:
CPI-SC0C3E2D267 F10_aMb2 complex simple:P00742 complex:aMb2 complex ENSG00000126218 True False False curated ,,,

Would you please tell me what they mean? Thank you very much.

@ShellyCoder
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attention

@keenhl
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keenhl commented Nov 15, 2019

I think it means, and I could definitely be wrong, that there is a receptor-receptor or ligand-ligand interaction. For example, there are a lot of receptors can that make hetero-dimers.

@Momomocheng
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Momomocheng commented Jul 31, 2020

#17

@mief mief closed this as completed Nov 4, 2020
@youarespecial
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Sorry , I still don't understand how to understand this ? Can someone explain it more clearly?

@keenhl
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keenhl commented Jun 11, 2021

@youarespecial Can you explain specifically what you didn't understand? Thanks.

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6 participants