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IshaanSD committed Oct 9, 2021
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### Welcome to the Crash Course!

This course is designed for individuals with zero to some programming experience and zero to some bioinformatics experience. It is ideally offered as a series of in-person workshops, specifically for students at UC San Diego to enable them to do research and projects like [modeling Cancer type from gene expression levels](/source/8_Classification_PCA.md), and get some exposure before taking upper-div classes.
This course is designed for individuals with zero to some programming experience and zero to some bioinformatics experience. It is ideally offered as a series of in-person workshops, specifically for students at UC San Diego to enable them to do research and projects like [modeling Cancer type from gene expression levels](https://www.bioinformaticscrashcourse.com/8_Classification_PCA.html), and get some exposure before taking upper-div classes.

Regardless, we hope that the material here is useful even if you are not able to complete all the exercises.

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*Note: In this course, we try to avoid lecture-based or text-heavy material. However, in this first lesson, we want to set a foundation of major problems bioinformaticians work on. We'll keep it short, and move on to the interactive part: working in a Linux environment!*

### I. The Alignment Problem ([full lesson](/source/10.1_Alignment.md))
### I. The Alignment Problem ([full lesson](https://www.bioinformaticscrashcourse.com/10.1_Alignment.html))

The first problem we'll look at is alignment. **Alignment is the process of arranging sequences in a way to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences.** In order to understand why alignment is hard and practical problem, we will start by learning a bit about sequencing DNA.

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