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########################## | ||
Frequently Asked Questions | ||
########################## | ||
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*************************** | ||
Why is `chess sim` so slow? | ||
*************************** | ||
A common cause for long runtimes of `chess sim` is when the input files are | ||
in `Cooler <https://github.com/mirnylab/cooler>`_ format. `chess sim` compares | ||
observed/expected transformed matrices, and these are often not precomputed | ||
and stored in this format. If your runs spend a long time in the | ||
"INFO Loading query contact data" step, consider converting your data to | ||
`Juicer <https://github.com/aidenlab/juicer>`_, or `FANC <https://github.com/vaquerizaslab/fanc>`_ | ||
format, as these usually store observed/expected values | ||
(see `here <https://fan-c.readthedocs.io/en/latest/fanc-executable/compatibility.html#cooler-cool-and-mcool>`_). |
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