Pan-Cancer Analysis Shows TP53 Mutations Modulate the Association of NOX4 with Genetic Programs of Cancer Progression and Clinical Outcome
R Code and Misc Files for Ma, Boudreau, Leto 2021 publication in Antioxidant.
Important Notes:
- Please set the working directory in the R script to a folder of your choosing. If you do not know how to do that, you may simply create a folder named R-Cache on your desktop and it will run smoothly.
- Please put the three required files in your working directory. Gene expression data from Broad Firehose will be downloaded automatically but annotation data must be imported locally.
- Please ensure that you have installed all the indicated libraries needed for the script. Refer to the top of the script for details.
- Contact me at weima@virginia.edu or weimasemail@gmail.com if you have trouble running the script.
- The analysis is divided into several individual scripts to promote efficiency- so that you don't have to run the entire analysis if you just want to reproduce a portion of the data. Please read the file name to determine which section is relavent to your interests.