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Physics-based 3D tomography Multi-slice neural network(MSNN)

torch(python) implementation of paper: Refractive index tomography with a physics based optical neural network. This GitHub provides the codes, and links to test data.

citation

If you use this project in your own research, please cite our corresponding paper:

Delong Yang, Shaohui Zhang, Yao Hu and Qun Hao, Refractive index tomography with a physics based optical neural network

Abstract

we demonstrate an untrained physics-based 3D tomography multi-slice neural network (MSNN), in which each layer has a clear corresponding physical meaning according to the beam propagation model. The network does not require pre-training and performs good generalization and can be recovered through the optimization of a set of actually acquired intensity images. Concurrently, MSNN can calibrate the intensity of different illumination and the multiple backscattering effects have also been taken into consideration by asserting a "scattering attenuation layer" between adjacent "refractive index" layers in the MSNN. The experiments have been conducted carefully to demonstrate the effectiveness and feasibility of the proposed method.

Requirement

numpy, pytorch(Minimum version 1.7.0), cuda11.1,opencv-python, matplotlib, scipy.

Usage

Run experiment.py to run the MSNN for C.elegan 3D tomography, the data of C.elegan is from Professor Laura Waller's Lab. If you want to use this code to reconstruct your own data, please carefully adjust the parameters in config.py to fit your optical system configuration.

Result

The reconstruction results with TV regularization are save in the folder IMG.

License

This project is licensed under the terms of the BSD-3-Clause license.

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Experiment demo for C.elegan.

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