Circulating polyunsaturated fatty acids and COVID-19: a prospective cohort study and Mendelian randomization analysis

(18th of June 2021)

Circulating polyunsaturated fatty acids and COVID-19: a prospective cohort study and Mendelian randomization analysis is unpublished.

Introduction

This directory contains supplementary code for our Mendelian randomization analysis to dissect causal effects of polyunsaturated fatty acids on COVID-19 using the TwoSampleMR R package by Yitang Sun and Kaixiong Ye.

Any of the most recent COVID-19 GWAS can be used in the code to apply MR analyses.

Download

Download all files from the github.

Mendelian randomization study

MR_forward.r

You only need to change the pathway.

Getting help

Please use the Github Issue page if you have questions.

Citation

To cite in publications, please use:

Name		Name	Last commit message	Last commit date
Latest commit History 6 Commits
.gitattributes		.gitattributes
MR_forward.r		MR_forward.r
Plasma_AA_HGI_round_4_A2.txt		Plasma_AA_HGI_round_4_A2.txt
Plasma_AA_HGI_round_4_B1.txt		Plasma_AA_HGI_round_4_B1.txt
Plasma_AA_HGI_round_4_B2.txt		Plasma_AA_HGI_round_4_B2.txt
Plasma_AA_HGI_round_4_C2.txt		Plasma_AA_HGI_round_4_C2.txt
Plasma_AA_HGI_round_5_A2_eur.txt		Plasma_AA_HGI_round_5_A2_eur.txt
Plasma_AA_HGI_round_5_B1_eur.txt		Plasma_AA_HGI_round_5_B1_eur.txt
Plasma_AA_HGI_round_5_B2_eur.txt		Plasma_AA_HGI_round_5_B2_eur.txt
Plasma_AA_HGI_round_5_C2_eur.txt		Plasma_AA_HGI_round_5_C2_eur.txt
Plasma_ALA_HGI_round_4_A2.txt		Plasma_ALA_HGI_round_4_A2.txt
Plasma_ALA_HGI_round_4_B1.txt		Plasma_ALA_HGI_round_4_B1.txt
Plasma_ALA_HGI_round_4_B2.txt		Plasma_ALA_HGI_round_4_B2.txt
Plasma_ALA_HGI_round_4_C2.txt		Plasma_ALA_HGI_round_4_C2.txt
Plasma_ALA_HGI_round_5_A2_eur.txt		Plasma_ALA_HGI_round_5_A2_eur.txt
Plasma_ALA_HGI_round_5_B1_eur.txt		Plasma_ALA_HGI_round_5_B1_eur.txt
Plasma_ALA_HGI_round_5_B2_eur.txt		Plasma_ALA_HGI_round_5_B2_eur.txt
Plasma_ALA_HGI_round_5_C2_eur.txt		Plasma_ALA_HGI_round_5_C2_eur.txt
Plasma_DGLA_HGI_round_4_A2.txt		Plasma_DGLA_HGI_round_4_A2.txt
Plasma_DGLA_HGI_round_4_B1.txt		Plasma_DGLA_HGI_round_4_B1.txt
Plasma_DGLA_HGI_round_4_B2.txt		Plasma_DGLA_HGI_round_4_B2.txt
Plasma_DGLA_HGI_round_4_C2.txt		Plasma_DGLA_HGI_round_4_C2.txt
Plasma_DGLA_HGI_round_5_A2_eur.txt		Plasma_DGLA_HGI_round_5_A2_eur.txt
Plasma_DGLA_HGI_round_5_B1_eur.txt		Plasma_DGLA_HGI_round_5_B1_eur.txt
Plasma_DGLA_HGI_round_5_B2_eur.txt		Plasma_DGLA_HGI_round_5_B2_eur.txt
Plasma_DGLA_HGI_round_5_C2_eur.txt		Plasma_DGLA_HGI_round_5_C2_eur.txt
Plasma_DHA_HGI_round_4_A2.txt		Plasma_DHA_HGI_round_4_A2.txt
Plasma_DHA_HGI_round_4_B1.txt		Plasma_DHA_HGI_round_4_B1.txt
Plasma_DHA_HGI_round_4_B2.txt		Plasma_DHA_HGI_round_4_B2.txt
Plasma_DHA_HGI_round_4_C2.txt		Plasma_DHA_HGI_round_4_C2.txt
Plasma_DHA_HGI_round_5_A2_eur.txt		Plasma_DHA_HGI_round_5_A2_eur.txt
Plasma_DHA_HGI_round_5_B1_eur.txt		Plasma_DHA_HGI_round_5_B1_eur.txt
Plasma_DHA_HGI_round_5_B2_eur.txt		Plasma_DHA_HGI_round_5_B2_eur.txt
Plasma_DHA_HGI_round_5_C2_eur.txt		Plasma_DHA_HGI_round_5_C2_eur.txt
Plasma_DPA-n3_HGI_round_4_A2.txt		Plasma_DPA-n3_HGI_round_4_A2.txt
Plasma_DPA-n3_HGI_round_4_B1.txt		Plasma_DPA-n3_HGI_round_4_B1.txt
Plasma_DPA-n3_HGI_round_4_B2.txt		Plasma_DPA-n3_HGI_round_4_B2.txt
Plasma_DPA-n3_HGI_round_4_C2.txt		Plasma_DPA-n3_HGI_round_4_C2.txt
Plasma_DPA-n3_HGI_round_5_A2_eur.txt		Plasma_DPA-n3_HGI_round_5_A2_eur.txt
Plasma_DPA-n3_HGI_round_5_B1_eur.txt		Plasma_DPA-n3_HGI_round_5_B1_eur.txt
Plasma_DPA-n3_HGI_round_5_B2_eur.txt		Plasma_DPA-n3_HGI_round_5_B2_eur.txt
Plasma_DPA-n3_HGI_round_5_C2_eur.txt		Plasma_DPA-n3_HGI_round_5_C2_eur.txt
Plasma_GLA_HGI_round_4_A2.txt		Plasma_GLA_HGI_round_4_A2.txt
Plasma_GLA_HGI_round_4_B1.txt		Plasma_GLA_HGI_round_4_B1.txt
Plasma_GLA_HGI_round_4_B2.txt		Plasma_GLA_HGI_round_4_B2.txt
Plasma_GLA_HGI_round_4_C2.txt		Plasma_GLA_HGI_round_4_C2.txt
Plasma_GLA_HGI_round_5_A2_eur.txt		Plasma_GLA_HGI_round_5_A2_eur.txt
Plasma_GLA_HGI_round_5_B1_eur.txt		Plasma_GLA_HGI_round_5_B1_eur.txt
Plasma_GLA_HGI_round_5_B2_eur.txt		Plasma_GLA_HGI_round_5_B2_eur.txt
Plasma_GLA_HGI_round_5_C2_eur.txt		Plasma_GLA_HGI_round_5_C2_eur.txt
Plasma_LA_HGI_round_4_A2.txt		Plasma_LA_HGI_round_4_A2.txt
Plasma_LA_HGI_round_4_B1.txt		Plasma_LA_HGI_round_4_B1.txt
Plasma_LA_HGI_round_4_B2.txt		Plasma_LA_HGI_round_4_B2.txt
Plasma_LA_HGI_round_4_C2.txt		Plasma_LA_HGI_round_4_C2.txt
Plasma_LA_HGI_round_5_A2_eur.txt		Plasma_LA_HGI_round_5_A2_eur.txt
Plasma_LA_HGI_round_5_B1_eur.txt		Plasma_LA_HGI_round_5_B1_eur.txt
Plasma_LA_HGI_round_5_B2_eur.txt		Plasma_LA_HGI_round_5_B2_eur.txt
Plasma_LA_HGI_round_5_C2_eur.txt		Plasma_LA_HGI_round_5_C2_eur.txt
RBC_AA_HGI_round_4_A2.txt		RBC_AA_HGI_round_4_A2.txt
RBC_AA_HGI_round_4_B1.txt		RBC_AA_HGI_round_4_B1.txt
RBC_AA_HGI_round_4_B2.txt		RBC_AA_HGI_round_4_B2.txt
RBC_AA_HGI_round_4_C2.txt		RBC_AA_HGI_round_4_C2.txt
RBC_AA_HGI_round_5_A2_eur.txt		RBC_AA_HGI_round_5_A2_eur.txt
RBC_AA_HGI_round_5_B1_eur.txt		RBC_AA_HGI_round_5_B1_eur.txt
RBC_AA_HGI_round_5_B2_eur.txt		RBC_AA_HGI_round_5_B2_eur.txt
RBC_AA_HGI_round_5_C2_eur.txt		RBC_AA_HGI_round_5_C2_eur.txt
RBC_ALA_HGI_round_4_A2.txt		RBC_ALA_HGI_round_4_A2.txt
RBC_ALA_HGI_round_4_B1.txt		RBC_ALA_HGI_round_4_B1.txt
RBC_ALA_HGI_round_4_B2.txt		RBC_ALA_HGI_round_4_B2.txt
RBC_ALA_HGI_round_4_C2.txt		RBC_ALA_HGI_round_4_C2.txt
RBC_ALA_HGI_round_5_A2_eur.txt		RBC_ALA_HGI_round_5_A2_eur.txt
RBC_ALA_HGI_round_5_B1_eur.txt		RBC_ALA_HGI_round_5_B1_eur.txt
RBC_ALA_HGI_round_5_B2_eur.txt		RBC_ALA_HGI_round_5_B2_eur.txt
RBC_ALA_HGI_round_5_C2_eur.txt		RBC_ALA_HGI_round_5_C2_eur.txt
RBC_DGLA_HGI_round_4_A2.txt		RBC_DGLA_HGI_round_4_A2.txt
RBC_DGLA_HGI_round_4_B1.txt		RBC_DGLA_HGI_round_4_B1.txt
RBC_DGLA_HGI_round_4_B2.txt		RBC_DGLA_HGI_round_4_B2.txt
RBC_DGLA_HGI_round_4_C2.txt		RBC_DGLA_HGI_round_4_C2.txt
RBC_DGLA_HGI_round_5_A2_eur.txt		RBC_DGLA_HGI_round_5_A2_eur.txt
RBC_DGLA_HGI_round_5_B1_eur.txt		RBC_DGLA_HGI_round_5_B1_eur.txt
RBC_DGLA_HGI_round_5_B2_eur.txt		RBC_DGLA_HGI_round_5_B2_eur.txt
RBC_DGLA_HGI_round_5_C2_eur.txt		RBC_DGLA_HGI_round_5_C2_eur.txt
RBC_DPA-n3_HGI_round_4_A2.txt		RBC_DPA-n3_HGI_round_4_A2.txt
RBC_DPA-n3_HGI_round_4_B1.txt		RBC_DPA-n3_HGI_round_4_B1.txt
RBC_DPA-n3_HGI_round_4_B2.txt		RBC_DPA-n3_HGI_round_4_B2.txt
RBC_DPA-n3_HGI_round_4_C2.txt		RBC_DPA-n3_HGI_round_4_C2.txt
RBC_DPA-n3_HGI_round_5_A2_eur.txt		RBC_DPA-n3_HGI_round_5_A2_eur.txt
RBC_DPA-n3_HGI_round_5_B1_eur.txt		RBC_DPA-n3_HGI_round_5_B1_eur.txt
RBC_DPA-n3_HGI_round_5_B2_eur.txt		RBC_DPA-n3_HGI_round_5_B2_eur.txt
RBC_DPA-n3_HGI_round_5_C2_eur.txt		RBC_DPA-n3_HGI_round_5_C2_eur.txt
RBC_DTA_HGI_round_4_A2.txt		RBC_DTA_HGI_round_4_A2.txt
RBC_DTA_HGI_round_4_B1.txt		RBC_DTA_HGI_round_4_B1.txt
RBC_DTA_HGI_round_4_B2.txt		RBC_DTA_HGI_round_4_B2.txt
RBC_DTA_HGI_round_4_C2.txt		RBC_DTA_HGI_round_4_C2.txt
RBC_DTA_HGI_round_5_A2_eur.txt		RBC_DTA_HGI_round_5_A2_eur.txt
RBC_DTA_HGI_round_5_B1_eur.txt		RBC_DTA_HGI_round_5_B1_eur.txt
RBC_DTA_HGI_round_5_B2_eur.txt		RBC_DTA_HGI_round_5_B2_eur.txt
RBC_DTA_HGI_round_5_C2_eur.txt		RBC_DTA_HGI_round_5_C2_eur.txt
RBC_GLA_HGI_round_4_A2.txt		RBC_GLA_HGI_round_4_A2.txt
RBC_GLA_HGI_round_4_B1.txt		RBC_GLA_HGI_round_4_B1.txt

yitangsun/COVID19_PUFA_MR

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