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Simulate the effect of drugs during total intrevenous anesthesia

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Python_Anesthesia_Simulator

The Python Anesthesia Simulator (PAS) models the effect of drugs on physiological variables during total intravenous anesthesia. It is particularly dedicated to the control community, to be used as a benchmark for the design of multidrug controllers. The available drugs are Propofol, Remifentanil, and Norepinephrine, the outputs are the Bispectral index (BIS), Mean Arterial Pressure (MAP), Cardiac Output (CO), and Tolerance of Laryngoscopy (TOL). PAS includes different well-known models along with their uncertainties to simulate inter-patient variability. Blood loss can also be simulated to assess the controller's performance in a shock scenario. Finally, PAS includes standard disturbance profiles and metrics computation to facilitate the evaluation of the controller's performances.

Structure

.
├─── src
|   ├─── python_anesthesia_simulator           # Simulator library + metrics function
|
├── example            # example of controller test pipeline with the library 
├── ...
├── paper              # markdown paper for JOSS submition
├── ...
├── tests              # file for testing the package
├── ...
├── LICENSE
├── pyproject.toml      # packaging file
├── requirements.txt
├── README.md
└── .gitignore          

Installation

Download the git repository and use pip to install the package:

    git clone https://github.com/BobAubouin/Python_Anesthesia_Simulator.git
    pip install .\Python_Anesthesia_Simulator

The package can be imported in your python script with:

    import python_anesthesia_simulator as pas

Documentation

Available in the Documentation.pdf file.

License

GNU General Public License 3.0

Project status

Submitted to JOSS

Author

Bob Aubouin--Paitault

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Simulate the effect of drugs during total intrevenous anesthesia

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