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python toolkits and GUI for multi-patch whole-cell data analysis and visualization

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ZeitgeberH/patchview

PatchView

Python3.8 Documentation Status BSD-3-Clause

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PatchView perform data analysis and visualization on multi channel whole-cell recording (multi-patch) data, including firing pattern analysis, event analysis, synaptic connection detection, morphological analysis and more.

Features

PatchView integrates multiple open-source tools (see credit page) and wrap them using an intuitive graphic user interface (GUI). Thus users can perform most analysis quickly for the data collected in a typical patch-clamp experiment without installing Python and these tools or writing any Python scripts.

  • Importing both Heka data and Axon Instruments data. Exporting to Python pickle file or NWB (Neurodata Without Borders) file format.
  • Visualizing single and multiple traces with zoom, pan operations.
  • Automatically sorting experiments data according to predefined labels.
  • Performing analysis on intrinsic membrane properties, action potential detection, firing pattern analysis.
  • Synaptic connection analysis.
  • Visualizing and quantification of neuron's morphological reconstruction from Neurolucida

Citation

If you find our work useful for your research, please cite:

Hu et al., (2022). PatchView: A Python Package for Patch-clamp Data Analysis and Visualization. Journal of Open Source Software, 7(78), 4706, https://doi.org/10.21105/joss.04706