FunctionalConnectomeHubs

Date 11/4/2022

First revision date 30/7/2022

Final revision date 16/9/2022

E-mail: zhileixu@163.com

This repository provides code and source data that support the findings of the article entitled "Meta-connectomic analysis maps consistent, reproducible, and transcriptionally-relevant functional connectome hubs in the human brain" by Xu et al. (2022) Communications Biology

AHBAprocessed Folder:

The preprocessed AHBA dataset, downloaded from https://doi.org/10.6084/m9.figshare.6852911

BrainMask Folder:

The gray matter mask used in the article.

BrainSpanAtlas Folder:

The normalized BrainSpan Atlas dataset, downloaded from http://brainspan.org/static/download.html

Code Folder:

1. Resting-state Functional MRI Preprocessing:

   PIPE_Preproces.m

   RUN_Preproces.m

2. Functional Connectivity Strength (FCS):

   PIPE_FCS.m

   RUN_FCS.m

   RUN_ComputeAdjacentMatrix.m

   PIPE_Regression.m

   RUN_PoolMeasurement.m

   RUN_Regression.m

3. Random-Effects Meta-Analysis:

   PIPE_MetaAnalysis.m

   RUN_MetaAnalysis.m

   RUN_REMA.m

4. Mapping Seed-to-Whole-Brain Connectivity Profiles of Brain Hubs:

   PIPE_SeedBasedFC.m

   RUN_SeedBasedFC.m

5. Global Signal Localization (GSL):

   PIPE_GSL.m

   RUN_GSL.m

SurrogateMap Folder:

Code for generating surrogate maps of the hub distribution map in Figure 1c and SupplementaryFigure 10a.

Figure Folder:

Code, source NIfTI file, and source data of the Figures 1 to 6 and Supplementary Figures 1 to 11 in the article.